Диагностика и лечение перипротезной инфекции после эндопротезирования тазобедренного сустава (обзор литературы)
Автор: Дмитров И.А., Загородний Н.В., Оболенский В.Н., Леваль П.Ш., Захарян Н.Г., Апресян В.С., Панин М.А., Самкович Д.А., Алиев Р.Н., Григорян А.А.
Журнал: Вестник медицинского института "РЕАВИЗ": реабилитация, врач и здоровье @vestnik-reaviz
Рубрика: Клиническая медицина
Статья в выпуске: 6 (60), 2022 года.
Бесплатный доступ
Введение. Во всем мире частота выполняемых операций по поводу эндопротезирования тазобедренного сустава неуклонно растет и, хотя данная операция стала рутинной, вероятность развития послеоперационных осложнений достигает 4,3 % [1]. Наиболее опасным из них является инфекция в области эндопротеза и прилегающих к нему тканей, приводящая к снижению функции тазобедренного сустава и ухудшению качества жизни пациента, а в случаях отсутствия лечения - к генерализации инфекционного процесса. Своевременная диагностика и лечение инфекционного процесса и связанных с ним нарушений позволяет минимизировать неблагоприятные последствия перипротезной инфекции.Целью настоящего обзора является анализ современных методов диагностики и лечения перипротезной инфекции, возникшей после эндопротезирования тазобедренного сустава.Материалы и методы. Поиск тематической литературы осуществлялся по базам данных PubMed и Google Sholar.Результаты. Основные методы диагностики перипротезной инфекции включают: гистологическое и бактериологическое исследование биоптата, определение чувствительности к антибиотикам, анализ крови и синовиальной жидкости на содержание лейкоцитов, ИЛ-6, СРБ, ПЦР-диагностику инфекционных агентов. Лечение заключается в проведении ревизионного вмешательства и/или антибактериальной терапии.Заключение. Оптимальным методом диагностики перипротезной инфекции является бактериологическое исследование биоптатов, взятых интраоперационно. Предпочтительный метод лечения определяется тяжестью инфекционного поражения, степенью вовлечения прилегающих к эндопротезу тканей, коморбидным фоном пациента, природой инфекционного агента и включает повторное ревизионное вмешательство.
Эндопротезирование, тазобедренный сустав, перипротезная инфекция, биопсия
Короткий адрес: https://sciup.org/143179604
IDR: 143179604 | DOI: 10.20340/vmi-rvz.2022.6.CLIN.7
Список литературы Диагностика и лечение перипротезной инфекции после эндопротезирования тазобедренного сустава (обзор литературы)
- Слободской А.Б., Осинцев Е.Ю., Леженев А.Г. Осложнения после эндопротезирования тазобедренного сустава. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2011;3:59-63. [Slobodskoy AB, Osintsev EY, Lezhenev AG Complications after hip arthroplasty. Bulletin of Traumatology and Orthopedics named after N.N. Priorova. 2011;3:59-63. (In Russ)].
- Шералиев Т.У., Федоров Е.А., Гольник В.Н. Павлов Перипротезная инфекция при эндопротезировании тазобедренного сустава: особенности современной этиологии, проблемы и перспективы диагностики. Красноярск: Новосибирский научно-исследовательский институт травматологии и ортопедии им. Я.Л. Цивьяна, 2021:230. [Sheraliev T.U., Fedorov E.A., Golnik V.N. Pavlov Periprosthetic infection in hip replacement: features of modern etiology, problems and prospects of diagnosis. Krasnoyarsk: Novosibirsk Scientific Research Institute of Traumatology and Orthopedics named after Ya. L. Tsivyan, 2021:230. (In Russ)].
- Середа А.П., Кочиш А.А., Черный А.А. и др. Эпидемиология эндопротезирования тазобедренного и коленного суставов и перипротезной инфекции в Российской Федерации. Травматология и ортопедия России. 2021;27(3):84-93. [Sereda AP, Kochish AA, Cherny AA, et al. Epidemiology of hip and knee arthroplasty and periprosthetic infection in the Russian Federation. Traumatology and Orthopedics of Russia. 2021;27(3):84-93. (In Russ)].
- Венедиктова А.А., Квашнина Д.В., Благонравова А.С. Факторы риска развития перипротезной инфекции по данным систематического обзора. Медицинский альманах. 2018;55(4):133-137. [Venediktova A.A., Kvashnina D.V., Blagonravova A.S. Risk factors for the development of periprosthetic infection according to a systematic review. Medical almanac. 2018;55(4):133-137. (In Russ)].
- Слободской А.Б., Осинцев Е.Ю., Лежнев А.Г. и др. Факторы риска развития перипротезной инфекции после эндопротезирования крупных суставов. Вестик травматологии и ортопедии им. Н.Н. Приорова. 2015;2:13-18. [Slobodskoy AB, Osintsev EY, Lezhnev AG, etc. Risk factors for periprosthetic infection after large joint endoprothesis. Vestik traumatology and orthopedics named after N.N. Priorova. 2015;2:13-18. (In Russ)].
- Мясоедов А.А., Торопов С.С, Березин Г.В. Факторы риска развития перипротезной инфекции после первичного эндопротезирования тазобедренного сустава. Травматология и ортопедия России. 2020;26(1):40-47. [Myasoedov AA, Toropov S, Berezin GV Risk factors for periprosthetic infection after primary hip endo-prosthetics. Traumatology and Orthopedics of Russia. 2020;26(1):40-47. (In Russ)].
- Seneviratne CJ, Yip JW, Chang JW et al. Effect of culture media and nutrients on biofilm growth kinetics of laboratory and clinical strains of Enterococcus faecalis. Arch Oral Biol. 2013;58:1327-1334.
- Berbari EF, Hanssen AD, Duffy MC et al. Risk factors for prosthetic joint infection: case-control study. Clin. Infect. Dis. 1998;27:1247-1254.
- Bongartz T, Halligan CS, Osmon DR et al. Incidence and risk factors ofprosthetic joint infection after total hip or knee replacement in patients with rheumatoid arthritis. Arthritis Rheum. 2008;59:1713-1720.
- Cipriano CA, Brown NM, Michael AM et al. Serum and synovial fluid analysis for diagnosing chronic periprosthetic infection in patients with inflammatory arthritis. J. Bone Joint Surg. Am. 2012;94:594-600.
- Berbari EF, Osmon DR, Carr A et al. Dental procedures as risk factors for prosthetic hip or knee infection: a hospital-based prospective case-control study. Clin. Infect. Dis. 2010;50:8-16.
- Dale H, Fenstad AM, Hallan G et al. Increasing risk of prosthetic joint infection after total hip arthroplasty. Acta Orthop. 2012;83:449-458.
- Peersman G, Laskin R, Davis J et al. Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin. Orthop. Relat. Res. 2001;392:15-23.
- Aslam S, Reitman C, Darouiche RO Risk factors for subsequent diagnosis ofprosthetic joint infection. Infect. Control Hosp. Epidemiol. 2010;31:298-301.
- Namba RS, Inacio MC, Paxton EW et al. Risk factors associated with deep surgical site infections after primary total knee arthroplasty: an analysis of 56,216 knees. J. Bone Joint Surg. Am. 2013;95:775-782.
- Pulido L, Ghanem E, Joshi A et al. Periprosthetic joint infection: the incidence, timing, and predisposing factors. Clin. Orthop. Relat. Res. 2008;466:1710-1715.
- Berbari EF, Osmon DR, Lahr B et al. The Mayo prosthetic joint infection risk score: implication for surgical site infection reporting and risk stratification. Infect. Control Hosp. Epidemiol. 2012;33:774-781.
- Duff GP, Lachiewicz PF, Kelley SS. Aspiration of the knee joint before revision arthroplasty. Clin. Orthop. Relat. Res. 1996;331:132-139.
- Peel TN, Cheng AC, Buising KL et al. Microbiological etiology, epidemiology, and clinical profile of prosthetic joint infections: are current antibiotic prophylaxis guidelines effective? Antimicrob. Agents Chemother. 2012;56:2386-2391.
- Coventry MB. Treatment of infections occurring in total hip surgery. Orthop Clin North Am. 1975 Oct;6(4):991-1003.
- Tsukayama DT, Estrada R, Gustilo RB. Infection after total hip arthroplasty. A study of the treatment ofone hundred and six infections. J. Bone Joint Surg. Am. 1996;78:512-523.
- Артюх В.А., Божкова С.А. Лечение параэндопротезной инфекции тазобедренного сустава. Клинические рекомендации. Санкт-Петербург: ФГБУ «РНИИТО им. Р.Р. Вредена» МЗ РФ. 2013:15. [Artyukh V.A., Bozhkova S.A. Treatment of paraendo-prosthetic infection of the hip joint. Clinical guidelines. St. Petersburg: FGBU "RNIITO named after R.R. Wreden" Ministry of Health of the Russian Federation. 2013:15. (In Russ)].
- Цискарашвили А.В., Загородний Н.В., Горбатюк Д.С. Культуроотрицательные биопленочные инфекции в ортопедиеской хирургии. Москва : ГЭОТАР-Медиа, 2021:208. [Tsiskarashvili A.V., Zagorodny N.V., Gorbatyuk D.S. Culture-negative biofilm infections in orthopedic surgery. Moscow: GEOTAR-Media, 2021:208. (In Russ)].
- Magill S.S., O'Leary E., Janelle S.J. et al. Emerging Infections Program Hospital Prevalence Survey Team. Changes in Prevalence of Health Care-Associated Infections in U.S. Hospitals. N. Engl. J. Med. 2018;379(18):1732-1744. https://doi.org/10.1056/ NEJMoa1801550
- Uckay I, Lubbeke A, Emonet S et al. Low incidence of haematogenous seeding to total hip and knee prostheses in patients with remote infections. J. Infect. 2009;59:337-345.
- Murdoch DR, Roberts SA, Fowler VG et al. Infection of orthopedic prostheses after Staphylococcus aureus bacteremia. Clin. Infect. Dis. 2001;32:647-649.
- Sendi P, Banderet F, Graber P et al. Periprosthetic joint infection following Staphylococcus aureus bacteremia. J. Infect. 2011 ;63:17-22.
- Tande AJ, Palraj B, Berbari E et al. Clinical Presentation, Risk Factors, and Outcomes of Hematogenous Prosthetic Joint Infection in Patients with Staphylococcus aureus Bacteremia. The American journal of medicine. 2016;129(2):221.е11 -20.
- Гостев В.В., Науменко З.С., Мартель И.И. Микрофлора ран открытых переломов различной локализации. Травматология и ортопедия России. 2008;50(4):63-67. [Gostev V.V., Naumenko Z.S., Martel I.I. Miflora wounds of open fractures of various localization. Traumatolo-giya and orthopedics of Russia. 2008;50(4):63-67. (In Russ)].
- Ерюхин И.А., Хрупкин В.А., Бадиков В.М. Хирургические инфекции: руководство. Санкт-Петербург, 2003:213-262. [Yeryu-khin I.A., Khraphkin V.A., Badikov V.M. Surgical infections: guidance. St. Petersburg, 2003: 213-262. (In Russ)].
- Ильина Т.С., Романова Ю.М., Гинцбург А.Л. Биопленки как способ существования бактерий в окружающей среде и организме хозяина: феномен, генетический контроль и системы регуляции их развития. Гзнетика. 2004;40:1-12. [Ilyina TS, Romanova JM, Gunzburg AL Biofilms as a way for bacteria to exist in the environment and host or-organism: a phenomenon, genetic control and systems for regulating their development. Genetics. 2004;40:1-12. (In Russ)].
- Donlan RM, Costerton JW. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 2002;15:167-193.
- Parvizi J, Zmistowski B, Berbari EF et al. New definition for periprosthetic joint infection: from the Workgroup of the Musculoskeletal Infection Society. Clin. Orthop. Relat. Res. 2011;469:2992-2994.
- Berbari E, Mabry T, Tsaras G et al. Inflammatory blood laboratory levels as markers of prosthetic joint infection: a systematic review and metaanalysis. J. Bone Joint Surg. Am. 2010;92:2102-2109.
- Bottner F, Wegner A, Winkelmann W et al. Interleukin-6, procalcitonin and TNF-alpha: markers of periprosthetic infection following total joint replacement. J. Bone Joint Surg. Br. 2007;89:94-99.
- Osmon DR, Berbari EF, Berendt AR et al. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin. Infect. Dis. 2013;56(1):e1-e25.
- Волошин В.П., Еремин А.В., Зубиков В.С. и др. Место цитологического исследования в диагностике и мониторинге пери-имплантного воспаления крупных суставов. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2013;1:58-62. [Voloshin V.P., Eremin A.V., Zubikov V.S., et al. Place of cytological examination in the diagnosis and monitoring of pe-riimplant inflammation of large joints. Bulletin of Traumatology and Orthopedics named after N.N. Priorova. 2013;1:58-62. (In Russ)].
- Кимайкина О.В., Григоричева Л.Г., Половцева А.В и др. Сравнительный анализ результатов определения цитоза в синовиальной и перипротезной жидкости микроскопическим методом и уровня лейкоцитов методом выявления лейкоцитэсте-разы. Журнал Медиаль. 2015;17(3):57. [Kimaykina O.V., Grigoricheva L.G., Polovtseva A.V., etc. Comparative Analysis of Cytosis Results in Syno-Vial and Periprosthetic Fluid by Microscopic Method and White Blood Cell Levels by Leukocytesis Terase Detection. Journal Medial. 2015;17(3):57. (In Russ)].
- Ghanem E, Parvizi J, Burnett RS et al. Cell count and differential of aspirated fluid in the diagnosis of infection at the site of total knee arthroplasty. J. Bone Joint Surg. Am. 2008;90:1637-1643.
- Parvizi J, Gehrke T. Proceedings of the International Consensus Meeting on periprosthetic joint infection. Musculoskeletal Infection Society, Rochester, MN: 2013.
- Parvizi J, Jacovides C, Antoci V et al. Diagnosis of periprosthetic joint infection: the utility of a simple yet unappreciated enzyme. J. Bone Joint Surg. Am. 2011;93:2242-2248.
- Deirmengian C, Hallab N, Tarabishy A et al. Synovial fluid biomarkers for periprosthetic infection. Clin. Orthop. Relat. Res. 2010;468:2017-2023.
- Jacovides CL, Parvizi J, Adeli B et al. Molecular markers for diagnosis of periprosthetic joint infection. Joint Arthroplasty. 2011 ;26:99-103.e101.
- Nilsdotter-Augustinsson A, Briheim G, Herder A et al. Inflammatory response in 85 patients with loosened hip prostheses: a prospective study comparing inflammatory markers in patients with aseptic and septic prosthetic loosening. ActaOrthop. 2007;78:629-639.
- Parvizi J, McKenzie JC, Cashman JP et al. Diagnosis of periprosthetic joint infection using synovial C-reactive protein. Joint Arthroplasty. 2012;27:12-16.
- Lee YS, Koo KH, Kim HJ et al. Synovial fluid biomarkers for the diagnosis of periprosthetic joint infection: a systematic review and meta-analysis. J Bone Joint Surg Am. 2017;99(24):2077-2084.
- Balato G., Franceschini V., Ascione T., Lamberti A., D'Amato M., Ensini A., Baldini A. High performance of a-defensin lateral flow assay (Synovasure) in the diagnosis of chronic knee prosthetic infections. Knee Surg. Sports Traumatol. Arthrosc. 2018;26(6):1717-1722. https://doi.org/10.1007/s00167-017-4745-x.
- Frangiamore S.J., Siqueira M.B., Saleh A., Daly T., Higuera C.A., Barsoum W.K. Synovial Cytokines and the MSIS Criteria Are Not Useful for Determining Infection Resolution After Periprosthetic Joint Infection Explantation. Clin Orthop Relat Res. 2016;474(7):1630-1639. https://doi.org/10.1007/s11999-016-4710-x. Erratum in: Clin. Orthop. Relat. Res. 2016 Jul;474(7):1740-1
- Shahi A., Parvizi J., Kazarian G.S., Higuera C., Frangiamore S., Bingham J., Beauchamp C., Valle C.D., Deirmengian C. The alpha-defensin test for periprosthetic joint infections is not affected by prior antibiotic administration. Clin. Orthop. Relat. Res. 2016;474:1610-5. https://doi.org/10.1007/s11999-016-4726-2
- Ali F, Wilkinson JM, Cooper JR et al. Accuracy of joint aspiration for the preoperative diagnosis of infection in total hip arthroplasty. J. Arthroplasty. 2006;21:221-226.
- Font-Vizcarra L, Garcia S, Martinez-Pastor JC et al. Blood culture flasks for culturing synovial fluid in prosthetic joint infections. Clin. Orthop. Relat. Res. 2010;468:2238-2243.
- Roberts P, Walters AJ, McMinn DJ et al. Diagnosing infection in hip replacements. The use of fine-needle aspiration and radiometric culture. J. Bone Joint Surg. Br. 1992;74:265-269.
- Fink B, Makowiak C, Fuerst M et al. The value of synovial biopsy, joint aspiration and C-reactive protein in the diagnosis of late periprosthetic infection of total knee replacements. J. Bone Joint Surg. Br. 2008;90:874-878.
- Atkins BL, Athanasou N, Deeks JJ et al. Prospective evaluation of criteria for microbiological diagnosis of prosthetic-joint infection at revision arthroplasty. J. Clin. Microbiol. 1998;36:2932-2939.
- Schafer P, Fink B, Sandow D et al. Prolonged bacterial culture to identify late periprosthetic joint infection: a promising strategy. Clin. Infect. Dis. 2008;47:1403-1409.
- Trampuz A, Piper KE, Jacobson MJ et al. Sonication of removed hip and knee prostheses for diagnosis of infection. N. Engl. J. Med. 2007;357:654-663.
- Оболенский В.Н., Семенистый А.А., Степаненко С.М. и др. Использование метода соникации в диагностике периимплант-ной инфекции. Клин. и эксперимент. хир.: журн. им. акад. Б.В. Петровского. 2016;2:104-109. [Obolensky V.N., Semenisty A.A., Stepanenko S.M., etc. Use of the sonication method in the diagnosis of peri-implant infection. Wedge. and the experiment. hir.: magazine. Academician B.V. Petrovsky. 2016;2:104-109. (In Russ)].
- Achermann Y, Vogt M, Leunig M et al. Improved diagnosis of periprosthetic joint infection by multiplex PCR of sonication fluid from removed implants. J. Clin. Microbiol. 2010;48:1208-1214.
- Bori G, Munoz-Mahamud E, Garcia S et al. Interface membrane is the best sample for histological study to diagnose prosthetic joint infection. Mod. Pathol. 2011;24:579-584.
- Cazanave C, Greenwood-Quaintance KE, Hanssen AD et al. Rapid molecular microbiologic diagnosis of prosthetic joint infection. J. Clin. Microbiol. 2013;51:2280-2287.
- Esteban J, Gomez-Barrena E, Cordero J et al. Evaluation of quantitative analysis of cultures from sonicated retrieved orthopedic implants in diagnosis of orthopedic infection. J. Clin. Microbiol. 2008;46:488-492.
- Holinka J, Bauer L, Hirschl AM et al. Sonication cultures of explanted components as an add-on test to routinely conducted microbiological diagnostics improve pathogen detection. J. Orthop. Res. 2011;29:617-622.
- Nguyen LL, Nelson CL, Saccente M et al. Detecting bacterial colonization of implanted orthopaedic devices by ultrasonication. Clin. Orthop. Relat. Res. 2002;403:29-37.
- Piper KE, Jacobson MJ, Cofield RH et al. Microbiologic diagnosis of prosthetic shoulder infection by use of implant sonication. J. Clin. Microbiol. 2009;47:1878-1884.
- Portillo ME, Salvado M, Trampuz A et al. Sonication versus vortexing of implants for diagnosis of prosthetic joint infection. J. Clin. Microbiol. 2013;51:591-594.
- Trampuz A, Piper KE, Hanssen AD et al. Sonication of explanted prosthetic components in bags for diagnosis of prosthetic joint infection is associated with risk of contamination. J. Clin. Microbiol. 2006;44:628-631.
- Vergidis P, Greenwood-Quaintance KE, Sanchez-Sotelo J et al. Implant sonication for the diagnosis of prosthetic elbow infection. J. Shoulder Elbow Surg. 2011;20:1275-1281.
- Feldman DS, Lonner JH, Desai P et al. The role of intraoperative frozen sections in revision total joint arthroplasty. J. Bone Joint Surg. Am. 1995;77:1807-1813.
- Mirra JM, Amstutz HC, Matos M et al. The pathology of the joint tissues and its clinical relevance in prosthesis failure. Clin. Orthop. Relat. Res. 1976;117:221-240.
- Mulcahy H, Chew FS et al. Current concepts of hip arthroplasty for radiologists: part 2, revisions and complications. AJR Am J Roentgenol. 2012;199(3):570-580.
- Leone S, Borre S, Monforte A et al. Consensus document on controversial issues in the diagnosis and treatment of prosthetic joint infections. Int. J. Infect. Dis. 2010;14(Suppl 4):S67-S77.
- Sewick A, Makani A, Wu C et al. Does dual antibiotic prophylaxis better prevent surgical site infections in total joint arthroplasty? Clin. Orthop. Relat. Res. 2012;470:2702-2707.
- Zimmerli W, Trampuz A, Ochsner PE. Prosthetic-joint infections. N. Engl. J. Med. 2004;351:1645-1654.
- Barberan J, Aguilar L, Carroquino G. Conservative treatment of staphylococcal prosthetic joint infections in elderly patients. Am. J. Med. 2006;119:993.e7-993.e10.
- Marculescu CE, Berbari EF, Hanssen AD et al. Outcome of prosthetic joint infections treated with debridement and retention of components. Clin. Infect. Dis. 2006;42:471-478.
- Jaen N, Martinez-Pastor JC, Munoz-Mahamud E et al. Long-term outcome of acute prosthetic joint infections due to Gram-negative bacilli treated with retention of prosthesis. Rev. Esp. Quimioter. 2012;25:194-198.
- Soriano A, Garcia S, Bori G et al. Treatment of acute post-surgical infection of joint arthroplasty. Clin. Microbiol. Infect. 2006;12:930-933.
- Byren I, Bejon P, Atkins BL et al. One hundred and twelve infected arthro- plasties treated with 'DAIR' (debridement, antibiotics and implant retention): antibiotic duration and outcome. J. Antimicrob. Chemother. 2009;63:1264-1271.
- Koyonos L, Zmistowski B, Della Valle CJ et al. Infection control rate of irrigation and debridement for periprosthetic joint infection. Clin. Orthop. Relat. Res. 2011;469:3043-3048.
- Azzam KA, Seeley M, Ghanem E et al. Irrigation and debridement in the management of prosthetic joint infection: traditional indications revisited. J. Arthroplasty. 2010;25:1022-1027.
- Brandt CM, Sistrunk WW, Duffy MC et al. Staphylococcus aureus prosthetic joint infection treated with debridement and prosthesis retention. Clin. Infect. Dis. 1997;24:914-919.
- El Helou OC, Berbari EF, Lahr BD et al. Efficacy and safety of rifampin containing regimen for staphylococcal prosthetic joint infections treated with debridement and retention. Eur. J. Clin. Microbiol. Infect. Dis. 2010;29:961-967.
- Zimmerli W, Widmer AF, Blatter M et al. Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. Foreign-Body Infection (FBI) Study Group. JAMA. 1998;279:1537-1541.
- Widmer AF, Frei R, Rajacic Z et al. Correlation between in vivo and in vitro efficacy of antimicrobial agents against foreign body infections. J. Infect. Dis. 1990;162:96-102.
- Tice AD, Hoaglund PA, Shoultz DA. Outcomes of osteomyelitis among patients treated with outpatient parenteral antimicrobial therapy. Am. J. Med. 2003;114:723-728.
- Klouche S, Leonard P, Zeller V et al. Infected total hip arthroplasty revision: one- or two-stage procedure? Orthop. Traumatol. Surg. Res. 2012;98:144-150.
- Ure KJ, Amstutz HC, Nasser S et al. Direct-exchange arthroplasty for the treatment of infection after total hip replacement. An average ten-year follow-up. J. Bone Joint Surg. Am. 1998;80:961-968.
- Buechel FF, Femino FP, D'Alessio J. Primary exchange revision arthroplasty for infected total knee replacement: a long-term study. Am. J. Orthop. 2004;33:190-198.
- Buchholz HW, Elson RA, Engelbrecht E et al. Management of deep infection of total hip replacement. J. Bone Joint Surg. Br. 1981;63:342-353.
- Callaghan JJ, Katz RP, Johnston RC. One-stage revision surgery of the infected hip. A minimum 10-year follow-up study. Clin. Orthop. Relat. Res. 1999;369:139-143.
- Engesaeter LB, Dale H, Schrama JC et al. Surgical procedures in the treatment of 784 infected THAs reported to the Norwegian Arthroplasty Register. Acta Orthop. 2011;82:530-537.
- Дзюба Г.Г., Резник Л.Б. Современные подходы к выполнению первого этапа ревизионного эндопротезирования тазобедренного сустава при поздних инфекционных осложнениях. Травматология и ортопедия России. 2009;3:127-129. [Dziuba GG, Reznik LB. Modern approaches to the implementation of the first stage of revision hip replacement in late infectious complications. Traumatology and Orthopedics of Russia. 2009;3:127-129. (In Russ)].
- Зазирный И.М. Лечение больных с инфекцией эндопротезированных коленных суставов. МатериалыРеспубл. науч.-практ. конф. с междунар. участием «Актуальные проблемы в травматологии и ортопедии». 2010;2:188-189. [Zazirny I.M. Treatment of patients with endoprosthetic knee joint infection. Respub materials. scientific - prakt. conf. with international participation "Actual problems in traumatology and orthopedics." 2010;2:188-189. (In Russ)].
- Bejon P, Berendt A, Atkins BL et al. Two-stage revision for prosthetic joint infection: predictors of outcome and the role of reimplantation microbiology. J. Antimicrob. Chemother. 2010;65:569-575.
- Mahmud T, Lyons MC, Naudie DD et al. Assessing the gold standard: a review of253 two-stage revisions for infected TKA. Clin. Orthop. Relat. Res. 2012;470:2730-2736.
- Dodson CC, Craig EV, Cordasco FA et al. Propionibacterium acnes infection after shoulder arthroplasty: a diagnostic challenge. J. Shoulder Elbow Surg. 2010; 19:303-307.
- Masri BA, Duncan CP, Beauchamp CP et al. Long-term elution of antibiotics from bone-cement: an in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system. J. Arthroplasty. 1998;13:331-338.
- Sterling GJ, Crawford S, Potter JH et al. The pharmacokinetics of Simplex-tobramycin bone cement. J. Bone Joint Surg. Br. 2003;85:646-649.
- Cui Q, Mihalko WM, Shields JS et al. Antibiotic-impregnated cement spacers for the treatment of infection associated with total hip or knee arthroplasty. J. Bone Joint Surg. Am. 2007;89:871-882.
- Pitto RP, Spika IA et al. Antibiotic-loaded bone cement spacers in two-stage management of infected total knee arthroplasty. Int. Orthop. 2004;28:129-133.
- Biring GS, Kostamo T, Garbuz DS et al. Two-stage revision arthroplastyofthe hip for infection usinganinterim articulated Prostalac hip spacer: a 10- to 15-year follow-up study. J. Bone Joint Surg. Br. 2009;91:1431-1437.
- Cabo J, Euba G, Saborido A et al. Clinical outcome and microbiological findings using antibiotic-loaded spacers in two-stage revision of prosthetic joint infections. J. Infect. 2011;63:23-31.
- Choi HR, Freiberg AA, Malchau H et al. The fate of unplanned retention of prosthetic articulating spacers for infected total hip and total knee arthroplasty. J. Arthroplasty. 2013;29(4):690-693.
- Petis SM, Abdel MP, Perry KI, Mabry TM, Hanssen AD, Berry DJ. Long-Term Results of a 2-Stage Exchange Protocol for Periprosthetic Joint Infection Following Total Hip Arthroplasty in 164 Hips. J Bone Joint Surg Am. 2019 Jan 2;101(1):74-84. https://doi.org/10.2106/JBJS.17.01103. PMID: 30601418
- Corró S, Vicente M, Rodríguez-Pardo D, Pigrau C, Lung M, Corona PS. Vancomycin-Gentamicin Prefabricated Spacers in 2-Stage Revision Arthroplasty for Chronic Hip and Knee Periprosthetic Joint Infection: Insights Into Reimplantation Microbiology and Outcomes. J Arthroplasty. 2020 Jan;35(1):247-254. https://doi.org/10.1016/j.arth.2019.07.043. Epub 2019 Aug 19. PMID: 31530462
- Tan TL, Kheir MM, Rondon AJ, Parvizi J, George J, Higuera C, Shohat N, Chen AF, Determining the Role and Duration of the "Antibiotic Holiday" Period in Periprosthetic Joint Infection. The Journal of Arthroplasty. 2018. https://doi.org/10.1016/j.arth.2018.04.019
- Klemt C, Smith EJ, Tirumala V, Bounajem G, van den Kieboom J, Kwon YM. Outcomes and Risk Factors Associated With 2-Stage Reimplantation Requiring an Interim Spacer Exchange for Periprosthetic Joint Infection. J Arthroplasty. 2021 Mar;36(3):1094-1100. https://doi.org/10.1016/j.arth.2020.09.012. Epub 2020 Sep 14. PMID: 33011012
- Santoso A, Yoon TR, Park KS, Anwar IB, Utomo P, Soetjahjo B, Sibarani T. The Results of Two-stage Revision for Methicillin-resistant Periprosthetic Joint Infection (PJI) of the Hip. Malays Orthop J. 2020 Mar;14(1):18-23. https://doi.org/10.5704/MOJ.2003.003. PMID: 32296477; PMCID: PMC7156181
- Osmanski-Zenk K, Klinder A, Rimke C, Wirtz DC, Lohmann CH, Haas H, Kladny B, Mittelmeier W. Evaluation of the standard procedure for treatment of periprosthetic joint infections of total knee and hip arthroplasty: a comparison of the 2015 and 2020 census in total joint replacement centres in Germany. BMCMusculoskeletDisord. 2021 Sep 15;22(1):791. https://doi.org/10.1186/s12891-021-04661-3. PMID: 34525989; PMCID: PMC8444384
- Lunz A, Omlor GW, Schmidt G, Moradi B, Lehner B, Streit MR. Quality of life, infection control, and complication rates using a novel custom-made articulating hip spacer during two-stage revision for periprosthetic joint infection. Arch Orthop Trauma Surg. 2021 Dec 1. https://doi.org/10.1007/s00402-021-04274-4. Epub ahead of print. PMID: 34853867
- Wroblewski BM. One-stage revision of infected cemented total hip arthroplasty. Clin. Orthop. Relat. Res. 1986;211:103-107.
- Berbari EF, Marculescu C, Sia I et al. Culture-negative prosthetic joint infection. Clin. Infect. Dis. 2007;45:1113-1119.
- Zmistowski B, Tetreault MW, Alijanipour P et al. Recurrent periprosthetic joint infection: persistent or new infection? J. Arthroplasty. 2013;28:1486-1489.
- Маловичко В.В., Уразгильдеев З.И., Цыкунов М.Б. Опорный неоартроз как альтернатива реэндопротезированию и артро-дезу при гнойных процессах в области тазобедренного сустава. Журнал «Вестник травматологии и ортопедии им. Н.Н. Приорова». 2003;2:48-56. [Malovichko V.V., Urazgildeev Z.I., Tsykunov M.B. Support neoarthrosis as an alternative to reendroplasty and art rhodesis in purulent processes in the hip joint. Journal "Bulletin of Traumatology and Orthopedics named after N.N. Priorova." 2003;2:48-56. (In Russ)].
- Castellanos J, Flores X, Llusa M et al. The Girdlestone pseudarthrosis in the treatment of infected hip replacements. Int. Orthop. 1998;22:178-181.
- Grauer JD, Amstutz HC, O'Carroll PF et al. Resection arthroplasty of the hip. J. Bone Joint Surg. Am. 1989;71:669-678.
- Хон В.Э., Загородний Н.В., Жадин А.В. и др. Роль операции Гирдлестоуна в лечении инфекционных осложнений после эндопротезирования тазобедренного сустава. Журнал «Вестник травматологии и ортопедии им. Н.Н. Приорова». 2013;3:25-31. [Hon WE, Zagorodniy NW, Zhadin AV, et al. The role of Girdlestone surgery in the treatment of infectious complications following hip arthroplasty. Journal "Bulletin of Traumatology and Orthopedics named after N.N. Priorova." 2013;3:25-31. (In Russ)].
- Krijnen MR, Wuisman PI. Emergency hemipelvectomy as a result of uncontrolled infection after total hip arthroplasty: two case reports. J. Arthroplasty. 2004;19:803-808.
- Sierra RJ, Trousdale RT, Pagnano MW. Above-the-knee amputation after a total knee replacement: prevalence, etiology, and functional outcome. J. Bone Joint Surg. Am. 2003;85:1000-1004.
- Pavoni GL, Giannella M, Falcone M et al. Conservative medical therapy of prosthetic joint infections: retrospective analysis of an 8-year experience. Clin. Microbiol. Infect. 2004;10:831-837.
- Bratzler DW, Dellinger EP, Olsen KM et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am. J. Health Syst. Pharm. 2013;70:195-283.
- Bode LG, Kluytmans JA, Wertheim HF et al. Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N. Engl. J. Med. 2010;362:9-17.
- Huang SS, Septimus E, Kleinman K et al. Targeted versus universal decolonization to prevent ICU infection. N. Engl. J. Med. 2013;368:2255-2265.
- AlBuhairan B, Hind D, Hutchinson A. Antibiotic prophylaxis for wound infections in total joint arthroplasty: a systematic review. J. Bone Joint Surg. Br. 2008;90:915-919.
- Hill C, Flamant R, Mazas F et al. Prophylactic cefazolin versus placebo in total hip replacement. Report of a multicentre double-blind randomised trial. Lancet. 1981;I:795-796.
- Park M, Markus P, Matesic D et al. Safety and effectiveness of a preoperative allergy clinic in decreasing vancomycin use in patients with a history of penicillin allergy. Ann. Allergy Asthma Immunol. 2006;97:681- 687.
- Meter JJ, Polly DW, Jr, Brueckner RP et al. Effect of intraoperative blood loss on the serum level of cefazolin in patients managed with total hip arthroplasty. A prospective, controlled study. J. Bone Joint Surg. Am. 1996;78:1201-1205.
- Программа СКАТ (Стратегия Контроля Антимикробной Терапии) при оказании стационарной медицинской помощи: Российские клинические рекомендации / под ред. С.В. Яковлева, Н.И. Брико, С.В. Сидоренко, Д.Н. Проценко. М.: Издательство «Перо», 2018:156. [SCAT program (Antimicrobial Therapy Control Strategy) in the provision of inpatient medical care: Russian clinical recommendations/ed. S.V. Yakovleva, N.I. Briko, S.V. Sidorenko, D.N. Protsenko. M.: Publishing house "Feather," 2018:156. (In Russ)].
- Lidwell OM, Lowbury EJ, Whyte W et al. Effect of ultraclean air in operating rooms on deep sepsis in the joint after total hip or knee replacement: a randomised study. BMJ. 1982;285:10-14.
- Jiranek WA, Hanssen AD, Greenwald AS. Antibiotic-loaded bone cement for infection prophylaxis in total joint replacement. J. Bone Joint Surg. Am. 2006;88:2487-2500.
- Parvizi J, Saleh KJ, Ragland PS et al. Efficacy of antibiotic-impregnated cement in total hip replacement. Acta Orthop. 2008;79:335-341.
- American Dental Association, American Academy of Orthopedic Surgeons. Antibiotic prophylaxis for dental patients with total joint replacements. J. Am. Dent. Assoc. 2003;134:895-899.
- Skaar DD, O'Connor H, Hodges JS et al. Dental procedures and subsequent prosthetic joint infections: findings from the Medicare Current Beneficiary Survey. J. Am. Dent. Assoc. 2011;142:1343-1351.