The dynamics of proviral load and antibody formation under experimental BLV infection in rats

The dynamics of antibody formation and proviral load under experimental BLV infection in laboratory rats was studied. It has been established that under parenteral BLV infection, productive infection develops in Wistar rats, elimination of the pathogen does not occur, the animals show a response by way of the antibody formation. Consequently, white laboratory rats of the Wistar line can be used as a laboratory model when studying the effects of the causative agent of bovine leukemia in vivo. At the same time, passage in the body of laboratory rats does not lead to a decrease in the infectivity of BLV for laboratory animals, and the offspring of infected rats have a more aggressive development of the infectious process than their parents.