Double-indicator radioisotope scanning in differential diagnostic of thyroid nodes

Purpose: To estimate diagnostic value of the method of double-indicator radioisotope scanning with 99mTc-pertechnetate and technetryl (99mTc-MIBI) in differencial diagnosis of benign and malignant thyroid nodes. Material and methods: The results of observation and treatment of 29 patients with thyroid nodes operated in surgical clinic were analyzed. Doubl-indicator scintygraphy with MIBI and puncture biopsy was made to all patients. Results: Results of scintygraphy were confirmed by histological and cytological methods. The fact that the node collected over 20% technetryl in comparison with normal tissue was considered positive result. Conclusions: Double-indicator radioisotope examination with 99mTc and Technetryl (99mTc-MIBI) is highly sensitive method of thyroid tumors diagnosis. Accuracy is 71%, specifity is 67%, and sensitivity is 76%. Higher effectiveness was found in diagnostic of papillary tumor.