Early and long-term outcomes of liver resections: a single specialized center experience

Early and long-term outcomes of liver resections: a single specialized center experience

Автор: Chichevatov D.A., Kalentjev V.V., Glukhov A.E., Seliverstova O.M., Rodina G.A., Tsyganova M.V.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Опыт работы онкологических учреждений

Статья в выпуске: 3 т.22, 2023 года.

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The purpose of the study was to evaluate the outcomes of a series of liver resections performed in a single regional specialized cancer center. Material and Methods. Eighty-nine patients underwent liver and/ or extrahepatic bile duct resections in the Penza Regional Oncology Hospital over the 8-year study period. Malignancies were observed in 81 patients. Extended liver resections (4 segments or more) were performed in 58 (65.2 %) cases. Results. Postsurgical morbidity and mortality rates were 31.5 % (28 of 89) and 6.7 % (6 of 89), respectively. Six of 10 patients with primary liver carcinomas were alive without evidence of disease progression at a follow-up time ranged from 1.0 to 76.7 months. Adjuvant chemotherapy (ACT) was the only predictor (HR=0.40; 95 % CI 0.16-0.98) of overall survival in patients with metastatic colorectal cancer (mCRC). The median survival time after liver resections for mCRC with or without ACT was 54.5 (95 % CI: 14.5-94.5) vs 21.8 months (95 % CI: 14.2-29.4), respectively. In mCRC patients with ACT, the 5-year overall survival rate was 44.8 ± 12.9 %. Conclusion. Primary hepatobiliary carcinomas and colorectal cancer liver metastases are the most common reasons for liver resections. A series of liver resections in a low-volume hospital is feasible with the achievement of good outcomes.

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Liver resection, malignant tumor, colorectal carcinoma, metastases

Короткий адрес: https://sciup.org/140300185

IDR: 140300185   |   DOI: 10.21294/1814-4861-2023-22-3-90-98

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