Estimation of the cardiovascular morbidity in the population of the Kabardino-Balkarian Republic according to the number of visits to health care offices

Автор: Kardangusheva Aksana M., Tkhabisimova Irina K., Budnik Antonina F., Shogenova Inessa Z., Sizhazheva Sofiat Kh.

Журнал: Cardiometry @cardiometry

Рубрика: Original research

Статья в выпуске: 17, 2020 года.

Бесплатный доступ

The aim is to evaluate the level, structure and dynamics of cardiovascular morbidity in the Kabardino-Balkarian Republic for the period from 2014 to 2019. The article describes the structure and dynamics of the general and primary morbidity of the adult population according to the main classes of diseases, the level, structure and dynamics of the general and primary morbidity of the circulatory system diseases from 2014 to 2019. The high prevalence of cerebrovascular disease and arterial hypertension, increase in new cases of acute myocardial infarction, postinfarction cardiosclerosis, cerebral infarction, intracerebral and other intracranial hemorrhage, the effects of cerebrovascular disease on the background of reducing the chronic forms of ischemic heart disease and arterial hypertension primary morbidity. The critical analysis of official statistics as a basis for management decisions is given. Scientific novelty of the work lies in the substantiation of reasonability of clinical and epidemiological research for the planning of preventive measures in the health-care system. As a result, reasonability of the clinical and epidemiological research and the need to implement additional preventive measures is substantiated.

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Morbidity, circulatory system diseases, cerebrovascular disease, ischemic heart disease, arterial hypertension

Короткий адрес: https://sciup.org/148311452

IDR: 148311452   |   DOI: 10.12710/cardiometry.2020.17.121126

Текст научной статьи Estimation of the cardiovascular morbidity in the population of the Kabardino-Balkarian Republic according to the number of visits to health care offices

Aksana M. Kardangusheva, Irina K. Tkhabisimova, Antonina F. Budnik, Inessa Z. Shogenova, Sofiat Kh. Sizhazheva. Estimation of the cardiovascular morbidity in the population of the Kabardino-Balkar- ian Republic according to the number of visits to health care offices. Cardiometry; Issue 17; November 2020; p.121-126; DOI: 10.12710/ cardiometry.2020.17.121126; Available from:

The cardiovascular diseases (CVD) are recognized by the international community as a challenge reaching a pandemic level. The epidemiological situation with the CVD cases in Russia is tighter as it is the case with other countries in the world that is evidenced by higher rates of morbidity and mortality from CVD, younger age of death caused by the CVD cases resulting in a decline in life expectancy. The existing unfavorable health care situation, of course, requires stronger attention to be paid to this problem [1,2,3]. No doubt that prevention, treatment and rehabilitation of the CVD patients are the most important components of maintaining the active longevity, saving labor potential and minimizing the social and economic burden caused by disability [1,4]. However, there are significant differences in the morbidity and mortality from CVD reported in some regions of the country. Therefore, it is important to analyze the existing epidemiological situation for the subsequent implementation of preventive programs adapted to the actual needs of the region.

The aim of the study is to estimate the level, structure and dynamics of the cardiovascular morbidity in the Kabardino-Balkarian Republic (KBR) within the period from 2014 to 2019.

Materials and methods

The study was conducted in the KBR, covering an area of 12 470 km2 with a population of 868 350 people as of January, 1, 2019. The region is divided into 3 urban districts and 10 municipal entities. The density of population in the Republic was 69.3 people per km2 with 52% of the urban population as of January 1, 2019 [5].

For our analysis we used data of State Health Care Institution "Medical Information and Analytical Center" at the KBR Ministry of Health Care. Morbidity rates were analyzed with descriptive statistics methods.

Results and discussion

In 2019 the rate of total morbidity was 86515.9 per 100 thousand population, the rate of the primary dis-

Issue 17. November 2020 | Cardiometry | 121

Dynamics of total and primary morbidity of the KBR population in 2014-2019 per 100 thousand adult population

Rates per 100 thousand

Year

territory

2014

2015

2016

2017

2018

2019

Total morbidity

RF

145477.3

144795.4

146341.7

146691.9

148941.1

150540.5

NCFD

115666.6

114768.0

117905.4

119822.7

117515.2

119865.7

KBR

106933.0

91035.5

90474.3

87609.2

87944.9

86515.9

Primary morbidity

RF

55259.5

54780.2

55227.3

54503.2

54734.2

54834.8

NCFD

50585.0

50248.0

49381.2

49631.8

47712.2

48965.2

KBR

31762.8

31647.8

30183.8

29867.1

30266.9

27647.5

Note: NCFD - the North Caucasian Federal District, RF - Russian Federation, KBR - the Kabardino-Balkarian Republic

Table 2

The structure of total and primary morbidity of the adult population according to the main classes of diseases in the KBR in 2019

Classes and groups of diseases

Morbidity per 100,000 adult population

Total

Primary

Sum-total

86515.9

27647.5

Certain infectious and parasitic diseases

1079.1

256.5

Neoplasms

3562.8

595.9

Diseases of blood, blood-forming organs and certain disorders involving the immune mechanism

424.9

77.6

Endocrine, nutritional and metabolic disorders

5470.1

631.5

Mental and behavioral disorders

3007.8

224.3

Nervous system diseases

4163.0

768.8

Diseases of the eye and adventitious apparatus

4181.2

1105.8

Diseases of the ear and mastoid

2695.4

1447.1

Circulatory system diseases

13771.8

1998.0

Respiratory diseases

12747.2

8386.7

Respiratory diseases

10350.6

1700.7

Diseases of the skin and subcutaneous tissue

2480.2

1728.9

Diseases of the musculoskeletal system and connective tissue

5580.0

814.1

Diseases of the genitourinary system

10359.4

2220.8

Pregnancy, childbirth and the postnatal period

7400.6

4409.7

Congenital anomalies (malformations), deformations and chromosomal abnormalities

29.9

1.5

Injuries, poisoning and other consequences of external causes

4326.8

4328.6

Note: NCFD - the North Caucasian Federal District, RF - Russian Federation, KBR - the Kabardino-Balkarian Republic ease 27647.5 per 100 thousand population (Table 1). In 2019, as compared with 2015, there was a decrease in the total morbidity by 5.0%, and primary by 12.6%, and when comparing 2019 with 2014, registered has been a decrease in the total morbidity by 19% and the primary by 13%.During the analyzed period the rates of total and primary morbidity in the KBR were lower than in the NCFD and RF, and decrease, in contrast to the NCFD and RF, where the morbidity increases (Table 1).

Such a difference can be caused by both the objective, related to the prevalence of various diseases, and the subjective, substantiated by the criteria of disease assessment and case management system, reasons. When analyzing the dynamics of morbidity it is also necessary to take into account that these rates are formed on the basis of the population appealability to 122 | Cardiometry | Issue 17. November 2020

public health facilities, where all cases are subject to registration and further accounting. Cases of appealability to the private health care institutions are not registered.

In 2019 the rate of the CSD total morbidity was 13771.8 per 100 thousand population, the primary morbidity 1998.0 per 100 thousand population (Table 2). In the structure of the total morbidity the traditional leader is the CSD, 16% in 2019. It is noteworthy that the diseases, which occupy the first three positions in the structure of morbidity (CSD, respiratory and digestive system diseases), are 42.6% of all diseases.

The CSD primary morbidity rate in 2019 in the KBR was 1998.0 per 100 thousand population. (2014 - 2503.4, a 505.4 decrease during 6 years). CBVDA-mong nosologic units the first place was occupied by the diseases characterized by the elevated blood pres-

The dynamics of the CSD primary morbidity in the KBR adult population for the period from 2014 to 2019 (per 100 thousand population)

Classes of diseases

Territory

Year

2014

2015

2016

2017

2018

2019

Circulatory system diseases (I00-I99)

RF

3357.5

3663.0

3754.0

3810.6

3897.3

4205.1

NCFD

4138.1

4343.5

3913.1

3651.0

3505.6

3895.6

KBR

2503.4

2330.6

2424.9

1950.9

1828.2

1998.0

Diseases characterized by high blood pressure (I10-I15)

RF

846.5

1105.7

1182.4

1201.3

1309.3

1472.2

NCFD

1096.2

1163.0

1157.4

881.0

1219.0

1326.4

KBR

858.6

827.5

861.6

779.4

620.1

767.8

Ischemic heart disease (I20-I25)

RF

834.7

911.0

876.0

918.9

893.2

932.4

NCFD

1313.0

1394.5

1045.7

929.0

807.7

896.0

KBR

448.7

481.8

459.2

367.0

366.2

388.2

Angina pectoris (I20)

RF

380.9

368.7

334.0

360.2

357.3

354.6

NCFD

843.4

734.0

526.9

390.4

409.2

477.8

131.5

109.7

99.5

103.4

62.3

111.1

Unstable angina (I20.0)

RF

138.14

169.20

149.1

168.4

149.9

143.0

NCFD

207.39

263.70

210.9

221.2

224.1

227.6

KBR

30.48

108.67

60.1

72.1

59.3

45.5

Acute myocardial infarction (I21)

RF

129.3

135.4

135.5

135.3

138.2

141.3

NCFD

83.3

95.7

85

90.3

98.9

105.7

KBR

44.7

74.5

67.7

133.3

162.1

131.7

Recurrent myocardial infarction (I22)

RF

25.07

24.47

24.04

23.13

21.7

19.6

NCFD

16.02

17.59

17.56

17.25

13.9

10.6

5.49

12.80

11.26

21.13

6.1

0.5

Other forms of acute ischemic heart disease (I24)

RF

11.59

16.98

17.12

14.77

14.8

13.9

NCFD

25.82

30.51

18.61

11.83

10.8

12.2

KBR

28.81

29.57

13.85

10.95

4.9

8.9

Chronic ischemic heart disease (I25)

RF

261.7

333.8

344.4

359.5

347.5

384.5

NCFD

313.3

309.1

290.5

209.7

255.0

272.6

KBR

211.6

196.0

188.3

98.2

130.8

136.0

Postinfarction cardiosclerosis (I25.2)

RF

81.5

93.2

90.4

93.6

96.8

102.2

NCFD

39.3

57.5

48.3

43.8

69.5

66.9

KBR

29.9

69.8

76.3

57.9

104.7

46.5

Cerebrovascular diseases (I60-69)

RF

822.3

901.6

949.0

947.8

973.0

995.8

NCFD

835.7

916.4

817.0

865.6

889.0

714.7

KBR

751.7

649.6

533.1

473.9

658.2

552.2

Subarachnoid hemorrhage (I60)

RF

10.80

13.67

188.3

98.2

13.9

10.7

NCFD

34.72

63.01

27.49

28.19

15.2

14.0

KBR

14.63

15.09

15.22

10.64

10.2

8.8

Intracerebral and other intracranial hemorrhage (I61-I62)

RF

38.96

42.74

42.38

44.20

43.2

41.3

NCFD

44.11

41.04

34.63

55.35

35.4

34.2

KBR

19.51

30.79

20.85

32.69

41.4

34.3

Cerebral infarction (I63)

RF

225.9

259.2

266.9

277.8

288.1

299.7

NCFD

164.1

208.4

190.6

216.7

227.0

205.8

KBR

50.8

168.4

168.3

211.5

225.7

242.7

Stroke, not clarified as hemorrhage or infarction (I64)

RF

46.59

39.37

31.73

29.00

25.1

21.6

NCFD

65.86

55.88

50.67

50.23

15.0

18.4

KBR

15.09

30.64

8.83

8.51

2.9

0.6

Other cerebrovascular diseases (I67)

RF

407.0

452.8

509.3

503.0

517.2

549.0

NCFD

412.2

405.1

398.5

397.7

379.9

357.6

KBR

633.1

381.0

308.8

154.9

349.9

229.9

Occlusion and stenosis of precerebral, cerebral arteries, not resulting in cerebral infarction

RF

14.68

15.27

15.93

18.60

14.6

16.0

NCFD

16.73

16.29

9.93

11.41

8.0

8.7

KBR

18.59

10.06

6.24

6.08

10.5

11.7

Consequences of cerebrovascular diseases (I69)

RF

78.4

78.6

65.8

56.8

60.4

57.5

NCFD

97.9

126.7

86.5

105.3

96.9

75.9

KBR

-

13.6

4.9

49.6

17.6

24.3

Note: NCFD - the North Caucasian Federal District, RF - Russian Federation, KBR - the Kabardino-Balkarian Republic

The dynamics of the CSD total morbidity in the KBR adult population for the period from 2014 to 2019 (per 100 thousand population)

Classes of diseases

Territory

Year

2014

2015

2016

2017

2018

2019

Circulatory system diseases (I00-I99)

RF

28247.4

28251.7

28897.8

29629.5

30698.5

31949.8

NCFD

18936.9

18227.7

19049.2

19183.8

19871.1

20574.6

KBR

19905.3

14574.5

13460.2

12829.9

13670.9

13771.8

Diseases characterized by high blood pressure (I10-I15)

RF

11280.8

11797.4

12358.4

12949.3

13810.0

14647.1

NCFD

7380.4

7588.5

8105.4

7556.2

8810.5

8640.0

KBR

9528.5

7318.0

6858.3

5971.8

6847.5

6313.4

Ischemic heart disease (I20-I25)

RF

6489.0

6425.2

6507.5

6622.3

6696.8

6902.7

NCFD

4784.3

4565.5

4717.9

4853.4

4727.4

5373.7

KBR

4134.9

2602.1

2572.9

2505.5

2588.3

2544.7

Angina pectoris (I20)

RF

2435.7

2384.3

2370.6

2410.7

2412.4

2431.0

NCFD

1827.5

1854.6

1739.3

2104.2

1926.7

2134.9

KBR

1429.2

1054.9

988.5

1018.4

1052.8

1052.6

Unstable angina (I20.0)

RF

138.14

169.30

149.07

168.42

149.9

143.0

NCFD

207.39

263.70

210.85

221.25

224.1

227.6

KBR

30.48

108.67

60.12

72.07

59.3

45.5

Acute myocardial infarction (I21)

RF

129.3

135.4

135.5

135.3

138.2

141.3

NCFD

83.3

95.7

85.0

90.3

98.9

105.7

KBR

44.7

74.5

67.7

133.3

162.1

131.7

Recurrent myocardial infarction (I22)

RF

25.07

24.47

24.0

23.1

21.7

19.6

NCFD

16.02

17.59

17.6

17.3

13.9

10.6

KBR

5.49

12.80

11.3

21.1

6.1

0.5

Other forms of acute ischemic heart disease (I24)

RF

22.78

19.49

17.1

14.8

14.8

13.9

NCFD

45.49

46.10

18.6

11.8

10.8

12.2

KBR

40.24

29.57

13.8

10.9

4.9

8.9

Chronic ischemic heart disease (I25)

RF

3757.8

3771.2

3862.1

3975.5

4036.6

4202.6

NCFD

2367.6

2250.5

2419.9

2582.6

2437.4

2596.2

KBR

2443.1

1174.4

1277.5

1321.7

1362.4

1331.3

Postinfarction cardiosclerosis (I25.2)

RF

618.5

661.9

701.9

719.1

741.8

782.5

NCFD

377.1

368.5

420.3

383.2

426.3

459.6

KBR

383.2

402.1

361.5

414.0

412.6

429.3

Cerebrovascular diseases (I60-69)

RF

6105.3

6030.2

5968.8

6035.4

6173.6

6262.2

NCFD

2687.3

2913.8

3086.5

3245.0

3307.0

3414.9

KBR

3157.9

2353.5

2044.3

2475.6

2767.3

2776.5

Subarachnoid hemorrhage (I60)

RF

10.80

13.67

11.7

14.1

13.9

10.7

NCFD

34.72

63.01

27.5

28.2

15.2

14.0

KBR

14.63

15.09

15.2

10.6

10.2

8.8

Intracerebral and other intracranial hemorrhage (I61-I62)

RF

38.96

42.74

42.4

44.2

43.2

41.3

NCFD

44.11

41.04

34.6

55.3

35.4

34.2

KBR

19.51

30.79

20.9

32.7

41.4

34.3

Cerebral infarction (I63)

RF

225.9

259.2

266.9

277.8

288.1

299.7

NCFD

164.1

208.4

190.6

216.7

227.0

205.8

KBR

50.8

168.4

168.3

211.5

225.7

242.7

Stroke, not clarified as hemorrhage or infarction (I64)

RF

46.6

39.4

31.7

29.0

25.1

21.6

NCFD

65.9

55.9

50.7

50.2

15.0

18.4

KBR

15.1

30.6

8.8

8.5

2.9

0.6

Other cerebrovascular diseases (I67)

RF

5688.1

5578.7

5500.3

5566.0

5688.0

5802.5

NCFD

2263.8

2398.8

2576.8

2712.0

2673.3

3014.4

KBR

3039.3

2058.1

1808.1

2141.1

2448.0

2440.6

Occlusion and stenosis of precerebral, cerebral arteries, not resulting in cerebral infarction

RF

16.49

17.89

21.98

26.45

24.0

28.9

NCFD

16.76

20.07

13.85

13.49

15.7

52.1

KBR

18.59

36.88

18.11

21.59

21.5

25.3

Consequences of cerebrovascular diseases (I69)

RF

78.4

78.6

65.8

56.8

60.4

57.5

NCFD

97.9

126.7

86.5

105.3

96.9

75.9

-

13.6

4.9

49.6

17.6

24.3

Note: NCFD - the North Caucasian Federal District, RF - Russian Federation, KBR - the Kabardino-Balkarian Republic sure (767.8 per 100 thousand population), the second place, by the cerebrovascular disease (CBVD, 552.2 per 100 thousand), the third by the ischemic heart disease (IHD, 388.2 per 100 thousand). The high arterial hypertension (AH), CBVD and IHD morbidity should be taken into account when designing specific measures aimed at improving the management of these patients cohorts and preventing the diseases.

Analysis of the dynamics of the primary and total morbidity (Table 3,4) in separate CSD showed an increase of newly diagnosed cases of acute myocardial infarction, postinfarction cardiosclerosis, cerebral infarction, intracerebral and other intracranial hemorrhage, CBVD consequences due to lower primary morbidity in chronic IHD, high blood pressure diseases, which should be considered in the planning of primary and secondary prevention of CSD. The highest rates of myocardial infarction, intracerebral and other intracranial hemorrhage occurred in 2018 with a slight decrease in 2019. Reducing the morbidity of stroke, not clarified as hemorrhage or infarction, occurred due to the improvement in the provision of specialized medical care at the stage of the hospital (widespread use of computed tomography, magnetic resonance imaging), which was achieved during the implementation of the regional program "Fight against cardiovascular disease in the Kabardino-Balkarian Republic “ and the organization of specialized medical care to patients with disorders of cerebral circulation in accordance with the order of Ministry of health of the Russian Federation No. 928-n, 2012 “Provision of specialized medical care in acute cerebral circulatory disorders”. A source of concern is the decrease in the primary and total morbidity of the diseases characterized by high blood pressure, with an increase in the morbidity of acute forms of IHD and CBVD, development and destabilization of which are pathogenetical-ly associated with AH.

Our study has some limitations. They consist in the fact that the study uses the data of official healthcare statistics, which only with certain restrictions can identify the problems which require efforts of the health-care system and other services for the planning of preventive work. When analyzing the results, relying only on official statistics, we failed at identifying the factors influencing the level and dynamics of disease. The reasons could be both objective, related to the prevalence of various diseases, and subjective, substantiated by the criteria of disease assessment and case management system. The rates of morbidity in the RF are formed on the basis of the population appealability to public health facilities, where all cases are subject to registration and further accounting. Cases of appealability to the private health care institutions are not registered. Therefore, the results of our study allowed us just to highlight the range of possible factors affecting the level and dynamics of disease. To estimate the true prevalence of diseases it is necessary to carry out simultaneous clinical and epidemiological studies in representative population samples with well-validated methods of examination and diagnostic criteria. Experience in the use of such studies results for prediction of health-care costs is accumulated in several countries [6]. Experience in the implementation of cross-sectional clinical and epidemiological studies exists both in the KBR and other regions of Russia [1,4,7]. However, it is not the rule in Russia to use these studies results in official reports on the health status of the population and in the planning of resource provision of medical care. However, it is known that the prevalence of one and the same disease is largely dependent on the studied sample, criteria and methods of evaluation. These factors should be considered when planning health care, especially expensive health care.

Conclusion

The CVD morbidity rates in the KBR are found to be below the national average level as well as below the NCFD rates, and they show their further tendency to decline. The implementation of the regional program "CVD control in the Kabardino-Balkarian Republic" has significantly improved the quality of rendering specialized medical service to the local population. However, the high prevalence of CBVD and AH, the growth of new cases of acute myocardial infarction, postinfarction cardiosclerosis, cerebral infarction, intracerebral and other intracranial hemorrhages, the consequences of CBVD against the background of lower primary case morbidity of chronic forms of ischemic heart disease, diseases characterized by high blood pressure, require the development and implementation of some additional measures for the early detection, primary and secondary prevention of CVDs focusing on the identification and control of AH. To optimize approaches to assessing the morbidity rate and prevalence of CVD, it is advisable to conduct an epidemiological study in the KBR, the results of which will allow us to identify the real prevalence of CVD and properly target the operation of health care facilities.

Statement on ethical issues

Research involving people and/or animals is in full compliance with current national and international ethical standards.

Conflict of interest

None declared.

Author contributions

The authors read the ICMJE criteria for authorship and approved the final manuscript.

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