Pharmacokinetics of molecular construction for deposition and transportation of biologically active substances to target cells
Автор: Gamaley S.G., Danilenko E.D., Bateneva A.V., Lebedev L.R., Masycheva V.I.
Журнал: Сибирский журнал клинической и экспериментальной медицины @cardiotomsk
Рубрика: Организация здравоохранения и общественное здоровье
Статья в выпуске: 3-2 т.23, 2008 года.
Бесплатный доступ
Studying pharmacokinetics of virus-like particle (VLP) marked by [gamma-32Р] was performed in non-inbred mice having transplanted solid Erlich carcinoma. VLP preparation was established to quickly eliminate from the blood and accumulate mainly in kidneys, spleen and intestine. The degree of accumulation of VLP in tumor tissue was higher than the preparation of comparison, double-stranded RNA. Preparation was eliminated from the organism of laboratory animals mostly via kidneys and completed by the end of the second day after the administration.
Virus-like particle, pharmacokinetics, ehrlich carcinoma, mice, dcrnk
Короткий адрес: https://sciup.org/14918915
IDR: 14918915
