The phenomenon of distant preconditioning. New approach to the protection of the organism during cardiac surgery

Operative interventions during cardiopulmonary bypass a accompanied by the organism's response to several pathological factors. Inadequate protection of the patients during cardiac operations leads to the development of the various dangerous complications. One of the promising approaches to the protection of the organism deals with the expression of endogenous mechanisms of stress protection, such as distant ischemic preconditioning (DIP). This article is viewing the mechanisms of its induction and the clinical use of DIP in patients during cardiac and vascular surgical procedures.