Physiological characteristics of platelets in Kholmogory calves during the phase of dairy and vegetable nutrition

In the work, the age-related dynamics of platelet activity in calves of the Kholmogory breed during the phase of milk and vegetable nutrition was evaluated. It has been established that in young animals of this breed at the age of 45 days, the process of platelet aggregation is accelerated, which is eliminated by 90 days of life. The number of inactive platelets in the blood of calves at 45 days decreased by 16.0 % and returned to the outcome by 90 days. At the same time, at the age of 45 days, they had a rapidly removable increase in the number of active platelets by 47.8 % and an increase in the content of small, as well as medium and large aggregates present in the blood, by 39.2 and 65.0 %, respectively. In the observed calves, by the 45th day of life, an intensification of thromboxane synthesis by 27.1 % was noted as a result of an increase in the activity of cyclooxygenase in them by 18.7 % and thromboxane synthetase by 25.7 %. In animals on the 45th day of life, a short-term increase in the amount of actin and myosin in platelets by 34.4 and 48.0 % was revealed. This was accompanied by an increase in the additional synthesis of actin and myosin by 23.3 and 26.9 %, respectively, during these periods of observation under conditions of platelet aggregation, which was eliminated by the end of the observation.