Influence of meta-chloro-benzhydryl urea on physiological and biochemical characteristics of Saussurea orgaadayi V. Khan. and Krasnob. cell culture

Meta-chloro-benzhydryl urea (m-СBU) is an inducer of the human monooxygenase system, its key enzymes belong to the cytochrome P-450 superfamily (CYP). Currently, there is no information about the role of m-СBU in the plant vital activity regulation; however, the participation of CYP in the metabolism of secondary metabolites, for example, flavonoids (Fl), and most phytohormones have been shown. Saussurea orgaadayi V. Khan. and Krasnob. is a poorly studied plant species. Its cell culture, in accordance with our data, doubles the total amount of endogenous Fl during the transition from exponential growth to the stationary phase. The present study, for the first time shows statistically significant (p