Flavonoids from leaves of Rhamnus pallasii Fisch. & C. A. Mey.

The article provides data on the qualitative composition of the flavonoids of the leaves of Rhamnus pallasii growing in Azerbaijan. In the alcoholic extract of Rhamnus pallasii leaves, collected at the beginning of flowering in the village of Amsar in the Quba district of Azerbaijan, by two-dimensional chromatography on paper in systems I and II, the presence of 9 compounds was found in the primary extract, of which 7 substances gave a characteristic reaction to flavonoids. It has been established that 5 of them are basic. Isolation of individual substances was carried out using column chromatography on polyamide. The structures of the isolated compounds were proved by the results of chromatography, spectral analysis, as well as the study of the products of acidic and enzymatic hydrolysis, alkaline melting and their comparison with the literature and reliable samples. Five individual substances were isolated, and they were identified as quercetin, kaempferol, isorhamnetin, rutin, isorhamnetin-3-glucoside. The results obtained make it possible to recommend the leaves of the plant as a source of raw materials for obtaining medicinal products and food additives.