The functional status of hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axis in young women with cardiovascular disease

Aim. The article aims to evaluate the functional status of the hypothalamic-pituitary-adrenocortical and hypothalamic-pituitary-gonadal systems in females with vascular dystonia from a special medical group. Materials and methods. The study involved first-year female students divided into 3 groups: 1 (control, n = 45) - apparently healthy students; 2 (experimental, n = 27) - students from a special medical group with vascular dystonia (VVD): 1st experimental (n = 12) - students diagnosed with VVD of the hypertensive type, 2nd experimental (n = 15) - students with VVD of the hypotonic type. The functional status of the hypothalamic-pituitary-adrenocortical and hypothalamic-pituitary-gonadal systems was revealed by the concentration of cortisol (K), testosterone (T) and estradiol (E) in saliva and the E / T ratio. Results. The content of cortisol in saliva in females with VVD in both experimental groups was significantly higher (P