Functional changes in the hepatobiliary system in patients with chronic coronary syndrome during antifungal therapy

Modern medicine is faced with the global challenge of multimorbidity. It is a combination of various visceral diseases, which affect the development and manifestation of the underlying disease. In elderly patients, pathologies are often combined with cardiovascular diseases, such as coronary artery disease. Coronary artery disease is usually treated with several drugs or their combinations, such as antianginal, antithrombotic, lipid-lowering, and cardiac metabolic drugs. However, these drugs are metabolized in the liver and may have a direct effect on it. Besides, combined treatment of two pathologies has a pronounced negative effect on the liver. The purpose of the study was to examine functional changes in the liver while treating patients with onychomycosis and coronary artery disease.