Hemorrhagic syndrome and hemostasis in children with acute lymphoblastic leukemia during the longterm chemotherapy

The hemorrhagic syndrome is one of frequent syndromes in acute lymphoblastic leukemia (ALL) children. This article presents the data of hemostasis studies on the basis of the program therapy with BFM90 in 53 ALL children. The failure of hemostasis in children with ALL was discovered before the treatment and increased during the program therapy. The study of the hemostasis is necessary for the prevention of hemorrhagic syndrome and its complications.