Генетически детерминированные тромбофилии в детском возрасте

Генетически детерминированные тромбофилии в детском возрасте

Автор: Жданова Л.В.

Журнал: Вестник Бурятского государственного университета. Философия @vestnik-bsu

Статья в выпуске: 12, 2015 года.

Бесплатный доступ

В статье представлен обзор литературы, посвященный наследственным тромбофилиям у детей. До настоящего времени нет единого мнения о вкладе генетических тромбофилий в развитие тромбоза у детей. Анализ литературных данных показывает, что при тромбозах у детей увеличивается встречаемость дефектных генов тромбофилий: Leiden мутация, мутация протромбина, полиморфизм C677T в гене метилентетрагидрофолатредуктазы, полиморфизм 4G/5G гена ингибитора плазминогена-1, что сопровождается возрастанием риска развития тромбозов.

Тромбофилии, дети, тромбозы, мутации, педиатрия, гипергомоцистеинемия

Короткий адрес: https://sciup.org/148182709

IDR: 148182709

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