Genetic factors of heart failure (review)

Heart failure (HF) is a highly prevalent syndrome characterized by etiological and clinical heterogeneity. This review highlights the genetic mechanisms underlying the development of this pathological condition. The results of recent genetic studies confirm the etiological complexity and clinical heterogeneity of HF. Identification of rare pathogenic variants underlying the development of HF among patients and their relatives is important for the timely adjustment of lifestyle and the implementation of preventive measures to reduce the risk of this syndrome and its complications.