Genetic thrombophilias and gestational complications

Автор: Momot A.P., Nikolaeva M.G.

Журнал: Вестник гематологии @bulletin-of-hematology

Рубрика: Передовая статья

Статья в выпуске: 4 т.16, 2020 года.

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The article presents modern ideas about thrombophilias caused, among other things, by mutations of factor V Leiden (FVL (1961) GA) and prothrombin G(20210) A and their role in the development of not only thrombotic but also gestational complications. The leading role of activated protein C resistance, prothrombin activity, as well as comorbidity in carriers of these prothrombogenic mutations has been determined. A tactic of anticoagulant prophylaxis has been proposed in order to reduce major placenta-mediated complications in carriers of these mutations

Мутация фактора v лейден f5l(1691) ga, мутация протромбина [f2g(20210) а], factor v leiden mutation fvl (1691) ga, prothrombin g (20210) a mutation, thromboembolic complications, placenta-mediated complications, comorbidity, apc-resistance, prothrombin activity

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Короткий адрес: https://sciup.org/170172550

IDR: 170172550

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