Hypotensive effect of renal denervation and its impact on left ventricular hypertrophy severity

The aim of the study was to evaluate long-term antihypertensive and cardioprotective efficacy of renal denervation in patients with drug-resistant arterial hypertension. The study excluded patients with symptomatic hypertension, multiple renal arteries when the diameter of one or more arteries was less than 3 mm, and patients with severe kidney disease stage 4-5. According to these criteria, 73 people were selected for renal denervation procedure. Comparison of the initial data with the values obtained after 12 months demonstrated the presence of a significant continuous antihypertensive effect with blood pressure decrease by -29.1/-14.8 mm Hg in the office blood pressure levels and by -12.9/-7.8 mm Hg according to 24-h monitoring. The study showed a decrease in the myocardial mass of the left ventricle in individuals who initially had more pronounced left ventricular hypertrophy.