Chemotherapy in the combined treatment of locally advanced bladder cancer

The combined treatment of locally advanced bladder cancer improves survival rates significantly, which is especially important for people of working age. The article deals with factors affecting overall and disease-free survival and compares various programs of systemic chemotherapy. The authors conclude that the early diagnosis and multimodality treatment for the locally advanced bladder cancer can achieve higher overall and disease-free survival, maintaining and sometimes improving the patients’ quality of life.