History of development of activation magnetic therapy of tumors and modern wave technologies. Dedicated to the memory of E. B. Kvakina and the 90th anniversary of her birth

National Medical Research Centre for Oncology, Rostov-on-Don, Rostov-on-Don, Russia

Elena B. Kvakina conducted her thorough, accurate studies on the mechanism of the antitumor effect produced by MP. It has been established that with the MP central (the brain-targeted) and local

(the tumor-targeted) impact, by a direct and a reflex effect, an increase in the functional state of the central nervous system takes place, in particular it refers to the hypothalamus, which causes an activation of its autonomic and endocrine parts. A change in the excitability of the nervous structures of the hypothalamus under the influence by AMF has been detected. Even a single AMF exposure resulted in lowering the threshold and led to an increase in the excitability of the hypothalamus that correlated with the data obtained with electroencephalographic research methods by Yu.A. Kholodov. Tissue respiration, oxidative phosphorylation and aerobic glycolysis of the hypothalamus with adjacent areas of the thalamus in rats of different groups, as well as the morphostructure of the hypothalamus under the brain exposure to AMF with the tumor regression cases were investigated. At the same time, a large number of thyrotrophs and luteinizing gonadotrophs were revealed in the adenohypophysis in rats with tumors, which resolved after the AMF head-targeted exposure. The functional state of the thyroid gland, the adrenal cortex, the thymic-lymphatic system and many other aspects has been investigated, confirming the activation nature of the magnetic action. In general, a huge database has been accumulated and comprehended confirming the safe and effective way of the contact-free exposure to MP that has played a decisive role in the translation of the developed intensity, frequency and exposure algorithms to the clinical departments at the Rostov-on-Don Oncology Center. The developed wave technologies were used in the complex treatment of skin cancer, lung cancer, malignant brain tumors, breast cancer, intestinal cancer and even hemangiomas in children under and over one year of age. The developments and advancements of the above researchers have been properly patented and doctoral and master’s theses have been successfully defended. Activation electromagnetic therapy of tumors is a unique product that has no analogues in the world. At the origins of its creation there were real patriotic scientists and great workers of science: Ukolova, Kvakina, Garkavi and their followers. We are grateful to our Cancer Center, to Prof. Oleg I. Kit, the General Director, Full Academician of the Russian Academy of Sciences, the committed research organizer, creating the friendliest environment for the development of the scientific break-through concept, when continuing the research into the influence made by magnetic fields, furnishing research labs with most advanced equipment and rendering full support to this priority area in science.