Immunobiological model of differential diagnosis of adjustment disorder and organic emotionally labile disorder

The relevance of the differential diagnosis of adjustment disorder and organic emotionally labile disorder is determined by the similarity of the clinical manifestations of these mental pathologies. In clinical practice, the emotional instability of patients in the organic register differs little from the emotional disturbances of patients with neurotic, stress-related disorders. These psychopathological conditions are combined with each other often, but in the interests of adequate therapeutic tactics, it is important to separate the main mental disorder and the cooccuring one. Research has accumulated on the interaction of the nervous and immune systems to date, showing the significant role of their close relationship in adjustment disorder and organic non-psychotic disorders. The search for additional biological criteria for the diagnostic delimitation of these disorders is a relevant scientific and clinical task.