Immunohistochemical exploration of jaw bone tissue defect after toothprotecting operations

Introduction. The article deals with the process of new bone formation within one year after toothprotecting operations. Various bone-seeking materials of autogenic, allogenic and xenogeneic origin are used in the process. The authors studied the cellular composition of the jaw postoperative defect for selecting the optimal osteoplastic filler in toothprotecting operations. Materials and Methods. 32 toothprotecting operations were carried out during the study period. The healthy jaw bone tissue was obtained during intake of teeth according to orthodontic indicators. The research was conducted using immunohistochemical methods in 3, 7, 30, 90, 120, 150, 180 and 360 days after operation. Results. Reduction of the number of CD68-positive cells is marker of proliferation of Ki-67 in the postoperation period. Discussion and Conclusions. The cell populations in the bone tissue defect are found in the state of active proliferation. The intensity of proliferative activity in groups of research decreases in the period after operation.