Indicators which are applied when assessing effects on a body exerted by nitrates and N-nitrosodimethylamine introduced with drinking water

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The authors comparatively assessed N-Nitrosodimethylamine (N-NDMA) contents in blood samples taken from children who consumed drinking water with increased nitrates and N-NDMA concentrations and in blood samples taken from children who consumed drinking water which fully corresponded to the existing hygienic standards; the article dwells on the results of this comparative assessment. We detected authentic discrepancies (р3) and the reference one (0.003 ± 0.0006 mg/dm3). We revealed that free-radical oxidation mechanisms were activated in children from the focus group who were exposed to N-NDMA. Lipids hydroperoxidation content in blood serum was proved to be 1.6 times higher in children from the focus group than in those from the reference one. When N-NDMA was detected in blood of children from the focus group, they ran 1.73 times higher risks of damages to their cells membranes...

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N-нитрозодиметиламин, nitrates, n-nitrosodimethylamine, drinking water, exposure indicator, indicator of an effect, odds ratio, specific sensitization

Короткий адрес: https://sciup.org/142215906

IDR: 142215906   |   DOI: 10.21668/health.risk/2018.3.08

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