Infective endocarditis as a cause of «KemCor» and «PeriCor» bioprostheses dysfunctions

We studied long-term results of «KemCor» and «PeriCor» epoxytreated bioprostheses implantation in 699 patients. Follow-up completeness was 72%, mean follow-up period 5.2±0.5 years. We found late prosthetic valve infective endocarditis (LPV IE) in 44 cases in 31.1±1.0 months of follow-up, and it formed 57% of all prosthetic dysfunction in the group. Overall LPV IE risk in the group was 7.04%; in parenteral drug abusers (n=40) it was as high as 22.5%, in «clear» valve disease 4.98%. LPV IE was more often seen in patients operated in active infective endocarditis (57%), and in villagers (71.4%). Reoperation rate was 88.6% (39 patients) with operative mortality rate 12.8%. In 5 cases the redo procedure was impossible. Conclusions. Implantation of epoxytreated «PeriCor» and «KemCor» bioprostheses shows low (8.5%) rate of prosthetic endocarditis in patients with infective endocarditis who are not parenteral drug abusers. In Siberan regions, late prosthetic valve endocarditis is a pressing problem therefore LPV IE prevention programs development is a necessity.