Studying the relationship of the polyphenoloxidase enzyme and the synthesis of radiotoxins in the irradiated organism

The aim of the study was to study the relationship between the activity of the polyphenol oxidase enzyme and the synthesis of radiotoxins in the irradiated animal organism. The experiments were carried out on laboratory animals - white rats, formed into groups depending on the radiation dose. The object of research was the liver of totally irradiated animals, which was examined for the activity of polyphenol oxidase by the colorimetric method and the formation of radiotoxins in the reaction of bentonite flocculation. It has been established that the activity of polyphenol oxidase after irradiation for a day first sharply increases, and starting from the 3rd day it drops sharply, while the concentration of radiotoxins, on the contrary, increases gradually and reaches its maximum by 7-10 days, when the polyphenol oxidase enzyme is inactivated. It has been shown that there is an inverse correlation between the studied biochemical parameters (polyphenol oxidase activity and radiotoxin concentration): the higher the polyphenol oxidase activity, the lower the radiotoxin concentration and vice versa.