Experimental basis of combined endoscopic correction of gastroduodenal perforation

To determine methods of combined endoscopic correction of gastroduodenal perforations three series of experiments and investigations on esophagogastric organs have been performed for the purpose to study technical possibilities of making hollow organ wall destruction and determination of technical parameters of endoscopic defect obturation. In the second series of experiments, possibility of gastroduodenal perforation modeling has been studied. In the third series of experiments, different methods of temporary obturation of gastroduodenal perforation foramens have been used. Results have been analyzed on the basis of intraoperative observation on the 1,2,3,7 and 14thdays after the endoscopic correction with the succeeding dynamic data evaluation of the obstruction zone endoscopic control. Combined endoscopic correction of perforation is used when surgery is contraindicated. It must be noted that, stomach drainage, pneumoperitoneum correction, sanation, perigastric region drainage and active aspiration of contained gastric juice can be used for the purpose of increasing efficiency of preoperative treatment. As a result of the research, special indications for the introduction of sutureless endoscopic methods for the gastroduodenal perforation treatment into clinical practice have been worked out.