Expression of regulatory t-cell markers FOXP3 and TGF-1 during viral infections, autoimmune diseases and cancer
Автор: Oleinik .., Oleinik V.., Churov .V., Bakhlaev I.., Kovchur P.I., Myasnikov .., Balashov ..
Рубрика: Влияние экологии на внутренние болезни
Статья в выпуске: 1-5 т.11, 2009 года.
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The functional activity of regulatory CD4+CD25+ Ò-cells was studied in patients with chronical viral infection, cancer and autoimmune pathology. The expression levels of forkhead box P3 (FOXP3), transforming growth factor-β1 (TGF-β1) and type II TGF-β1 receptor (TGF-βRII) as primary molecular markers of suppressor lymphocytes were also investigated. Significant elevation of expression of FOXP3 and TGF-β1 has been found in cancer and during chronical viral infection.
Molecular markers, lymphocytes, infections
Короткий адрес: https://sciup.org/14899863
IDR: 14899863
