Elemental markers of exposure under combined oral introduction of chemical mixtures with prevalent antimony and arsenic into white Wistar rats

The present paper dwells on assessing oral sub-acute exposure of a warm-blooded body to non-organic compounds that contain antimony and arsenic and are introduced with drinking water. Another issue was to assess changes in their concentrations as well as concentrations of other elements in tissues of certain organs. We accomplished elemental analysis of tissues taken from exposed white Wistar rats; the analysis included the following elements: S, Cl, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, Se, Br, Rb, Sr, Mo, As, Hg, Pb, Sb. As per its results we characterized changes in elemental structure of the liver, kidneys, heart, lungs, femoral muscle, thyroid gland, and whole blood caused in white male Wistar rats by sub-acute combined oral exposure to arsenic and antimony. Arsenic was detected in all the examined internal organs after 3 weeks of combined oral exposure to it in a dose equal to 15 µg/kg together with exposure to antimony in a dose equal to 61 µg/kg. It concerned both test and control group as animals in the test group had arsenic in a dose equal to 0...