The clinical efficacy of the ganglionated plexi ablation in patients with atrial fibrillation

The present article shows the analysis of the clinical efficacy of the radiofrequency ganglionated plexi ablation in patients with atrial fibrillation (AF). In our study we included 415 patients with paroxysmal atrial fibrillation (AF), who were undergone anatomical ablation of the ganglionated plexi. We revealed that freedom from atrial fibrillation at the long-term follow up was 81,9%, 80% and 61,9% in patients with paroxysmal, persistent and permanent forms respectively. The QOL score in patients with AF significantly increased after ganglionated plexi ablation based on SF-36 data. The multivariable analysis demonstrated the following predictors of late AF recurrence: atrial hypertension and hyperlipidemia, the left atrial volume more than 62 mm, BMI > 40 kg/m2, presence of AF more than 10 years and permanent AF lasting more than 3 years. In conclusion, the radiofrequency ablation of the AF is a high effective method in selected patients without extracardiac and structural heart diseases and permanent long-term AF. The early AF recurrence within 3 month after ablation can not be the criteria of inefficacy.