Clinical typology of withdrawal syndrome in dependence on synthetic cannabinoids (spice) in patients with paranoid schizophrenia

Introduction. Late detection, differentiation and treatment of withdrawal symptoms caused by synthetic cannabinoids (spice) in patients with paranoid schizophrenia interfere with their rehabilitation potential, lead to rehospitalization, as a result shorten remission, and reduce the statistical information content of this kind of drug dependence. The aim is to study the clinical picture of withdrawal syndrome in persons with paranoid schizophrenia who are dependent on synthetic cannabinoids (Spice). Methods: collection of anamnesis, follow-up history, clinical, psychopathological, statistical. Results. Symptoms of the endogenous process and symptoms of the withdrawal syndrome due to use of synthetic cannabinoids were differentiated. Variants of actualization of acute states catalyzed by Spice were described. The leading role in the separation of abstinence caused by the synthetic cannabinoids and the endogenous process was rendered by the ability of the states caused by Spice to virtually totally reduce the symptoms, against the background of the antipsychotic therapy, the instability of the psycho-production...