Asymptomatic thrombophilia in patients with skeletal trauma and cardiac pathology

We obtained data of coagulogram tests and platelet aggregation in patients with bone fractures during their in-patient stay and on follow-up and compared these data between the groups of patients with and without cardiac pathology. 106 patients were examined (58 of them were examined during their inpatient stay). Markers of thrombinemia were signifi-cantely increased in patients with fractures as compared to patients without fractures. Thrombophilyc changes were most noticeable when ischemic heart disease and cardiovascular risk factors were present in patients with fractures. Hemostasis subsystems is shown to take part in development of an acquired thrombophilia in an interdependent way.