The clinical relevance of laboratory values in determination of severity of myocardial infarction in hyperglicemic patients

The aim of the study was to assess the predictive implication of hyperglycemia and other laboratory values, which are commonly measured in clinical practice in groups of patients with myocardial infarction (MI) with and without diabetes mellitus. We performed the retrospective analysis of case reports of patients hospitalized with acute myocardial infarction (AMI) and with admission glycemic level >7.8 mmol/L. In the course of analysis we found that admission glycemic level and 2nd week glycemic level are associated with severity of acute and chronic systolic left ventricular disfunction and with development of CHF in patients with AMI without DM; high blood sugar level, leukocyte level and uric acid level in group of patients without DM can be used as predictors of severity of disease; the acute stress reaction to myocardial damage in a form of high level of glycaemia and leucocytosis have a greater degree in male without DM compared with patients with DM or female without DM; patients with first diagnosed DM are characterized by the greater degree of Creactive protein as reaction to myocardial damage compared with patients with previously diagnosed DM or patients without DM.