Clinical value of follicular fluid morphology in patients with inflammatory infertility genesis in outcome prognosis of assisted reproductive technology programs

The objective of the paper is to study the follicular fluid morphology in women with inflammatory infertility genesis, who were treated by means of assisted reproductive technologies (ART) and to show the dependence of ART prognostic outcomes on the level of follicular fluid structuredness. Materials and Methods. The authors studied follicular fluid morphology of 98 patients with inflammatory infertility genesis who were included in extracorporal fertilization and embryo transfer. Results. The study of follicular fluid morphology was conducted using the method of cuneate dehydration. Specific characteristics of facies patterns were identified. The authors defined 4 types of follicular fluid facies according certain markers, namely, definite disruptions. Moreover, new disruptions peculiar only to follicular fluid were revealed. The authors also described inflammatory markers, which determined the ovum toxicity level and ovarium readiness to be treated with ART methods. According to the definite pattern of the central facies zone it was possible to find out the endocrine profile in each patient after using multifollicular ovarian stimulation protocols. The authors defiend physiological and pathological facies state as well as stable and unstatble homeostasis. All these characteristics of facies patterns make it possible to determine the application of ART methods as favorable or unfavorable.