Clinical-dynamic features of affective disorders in their comorbidity with personality disorders

The present study investigates clinical and dynamic features of mood disorders comorbid with personality disorder. Total group of patients (n=50) with current moderate or severe depressive episode (F31, F32, F33) was divided into two matched by age, sex and diagnosis groups: main group (n=25) - presence of comorbidity with personality disorder (F60.31 ; F60.4; F61.0), comparison group (n=25) - patients without comorbid personality disorder. Assessment of severity of current depressive episode was made using SIGH-SAD. In main group, onset of affective disorder at a younger age, longer duration and greater severity of depressive episodes, more frequent recurrence of affective episodes, more severe atypical depressive symptoms and higher incidence rate of anxiety-dysphoric syndrome in structure of current depressive episode as compared with the corresponding indices in patients with affective disorders without presence of comorbidity with personality disorder have been noted.