Key genes and polymorphisms in urolithiasis associated with the formation of calcium oxalate, cystine and urate stones

Introduction. Urolithiasis is a multifactorial disease affecting all population groups. The incidence of urolithiasis in different countries varies from 1,7 to 14,8%. The risk of developing urolithiasis depends on age, gender, race, geographic location and hereditary predisposition, while 40-50% of patients have a burdened family history, so the search for genetic markers associated with urolithiasis is relevant.