Combination therapy of atrial fibrillation along with mitral valve disease

The article reveals the results of the usage of combination therapy of atrial fibrillation in the early postsurgical period in patients with mitral valve abnormality. The study included 34 patients. All patients were operated with mitral valve abnormality and underwent a procedure of radiofrequency atrial isolation «labyrinth». The initial group of patients along with operational treatment of mitral valve abnormality underwent sutural plastics of left atrium by self developed procedure. One year after the surgery, medium size of left atrium in the group with atrium plastics was 44,3±4,4 mm, left atrial volume - 118,39±22,4 ml, and in the group without atrial plastics - 46,7±2,7 mm and 152,6±34,2 ml respectively; the results between the groups authentically differed from each other. Absolute rhythm control in postsurgical period and conducting, if necessary, cardioversion at the time of 6-12 months with underlying antiarrhythmic therapy allows to increase patients' sinus rhythm rate up to 85%. Surgical reduction of left atrial chamber along with withdrawal of hemodynamic (mitral valve replacement) and electrophysiological reasons (procedure of radiofrequency atrial isolation «labyrinth») of atrial fibrillation will permit to increase significantly the frequency of postsurgical recovery and preservation of sinus rhythm, thereby, to improve long term prognosis of these patients.