Complex radial assesment of cerebroprotective efficacy of antihypertensive therapy using MR-tomography and perfusion HRCT of the brain

A multimodal MRI-DynCT study of the brain was performed in 22 patients with arterial hypertension (mean systolic arterial pressure = 152,8±7,6 mm Hg, mean diastolic arterial pressure = 94,6±5,2 mm Hg) without history of coronary or cerebral infarctions signs. Significantly decreased periventricual oedema and improved perfusion of basal ganglii area were revealed in patients who demonstrated decreased systolic apterial pressure by 12-28 mm Hg. MRI and DynCT in patients who demonstrated decrease in systolic arterial pressure over or below of the interval were seen after treatment essentially the same as at admission. Thus we conclude that the brain MRI and perfusion DynCT data can be employed for evaluation of cerebroprotective efficacy of antihypertensive therapy.