The condensation of aceton with diethyl oxalate and aryl diazonium salts

Ethyl 3-arylhydrazono-2,4-dioxopentanoates are obtained by the reaction 1-ethoxy-1,4-dioxo-2-penten-2-olyat sodium with aryl diazonium salts. «One-pot» three-component condensation of acetone with diethyl oxalate and aryl diazonium salts leading to formation еthyl 3-arylhydrazono-2,4-dioxopentanoates is studied. Structure peculiarities of the synthesized compounds are discussed in terms of UV, IR, NMR spectroscopy, and X-Ray diffraction. Antimicrobial activity of the synthesized compounds is investigated.