Конвекционно-усиленная доставка препаратов при диффузных внутренних глиомах моста головного мозга у детей и подростков
Автор: Регентова О.С., Пархоменко Р.А., Антоненко Ф.Ф., Зелинская Н.И., Сидибе Н., Шевцов А.И., Полушкин П.В., Близниченко М.А., Солодкий В.А.
Журнал: Вестник Российского научного центра рентгенорадиологии Минздрава России @vestnik-rncrr
Рубрика: Обзор
Статья в выпуске: 3 т.24, 2024 года.
Бесплатный доступ
Конвекционно-усиленная доставка препаратов - одна из новых методик проведения лекарственной терапии при диффузных внутренних глиомах моста головного мозга, при которых пока другими методами не удалось существенно улучшить весьма низкие показатели эффективности лечения. В обзоре обсуждаются результаты исследований по применению этой методики, полученные к настоящему времени.
Диффузные глиомы, лечение глиом, гематоэнцефалический барьер, химиопрепараты, способ введения препаратов
Короткий адрес: https://sciup.org/149146720
IDR: 149146720
Список литературы Конвекционно-усиленная доставка препаратов при диффузных внутренних глиомах моста головного мозга у детей и подростков
- Bailey S, Howman A, Wheatley K, Wherton D, Boota N, Pizer B, et al. Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy--results of a United Kingdom phase II trial (CNS 2007 04). Eur J Cancer. 2013 Dec;49(18):3856-3862. doi: 10.1016/j.ejca.2013.08.006.
- Chassot A, Canale S, Varlet P, Puget S, Roujeau T, Negretti L, et al. Radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma. J Neurooncol. 2012 Jan;106(2):399-407. doi: 10.1007/s11060-011-0681-7.
- Robison NJ, Kieran MW. Diffuse intrinsic pontine glioma: a reassessment. J Neurooncol. 2014 Aug;119(1):7-15. doi: 10.1007/s11060-014-1448-8.
- Tosi U, Souweidane M. Convection Enhanced Delivery for Diffuse Intrinsic Pontine Glioma: Review of a Single Institution Experience. Pharmaceutics. 2020 Jul 14;12(7):660. doi: 10.3390/pharmaceutics12070660.
- Farrukh S, Habib S, Rafaqat A, Sarfraz Z, Sarfraz A, Sarfraz M, et al. Emerging Therapeutic Strategies for Diffuse Intrinsic Pontine Glioma: A Systematic Review. Healthcare (Basel). 2023 Feb 13;11(4):559. doi: 10.3390/healthcare11040559.
- Sirachainan N, Pakakasama S, Visudithbhan A, Chiamchanya S, Tuntiyatorn L, Dhanachai M, et al. Concurrent radiotherapy with temozolomide followed by adjuvant temozolomide and cis-retinoic acid in children with diffuse intrinsic pontine glioma. Neuro Oncol. 2008 Aug;10(4):577-82. doi: 10.1215/15228517-2008-025.
- Kim CY, Kim SK, Phi JH, Lee MM, Kim IA, Kim IH, et al. A prospective study of temozolomide plus thalidomide during and after radiation therapy for pediatric diffuse pontine gliomas: preliminary results of the Korean Society for Pediatric Neuro-Oncology study. J Neurooncol. 2010 Nov;100(2):193-198. doi: 10.1007/s11060-010-0157-1.
- Wolff JE, Wagner S, Reinert C, Gnekow A, Kortmann RD, Kühl J, Van Gool SW. Maintenance treatment with interferon-gamma and low-dose cyclophosphamide for pediatric high-grade glioma. J Neurooncol. 2006 Sep;79(3):315-321. doi: 10.1007/s11060-006-9147-8.
- Wolff JE, Driever PH, Erdlenbruch B, Kortmann RD, Rutkowski S, Pietsch T, et al. Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol. Cancer. 2010 Feb 1;116(3):705-712. doi: 10.1002/cncr.24730.
- Korones DN, Fisher PG, Kretschmar C, Zhou T, Chen Z, Kepner J, Freeman C. Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: a Children's Oncology Group phase II study. Pediatr Blood Cancer. 2008 Feb;50(2):227-230. doi: 10.1002/pbc.21154.
- Massimino M, Spreafico F, Biassoni V, Simonetti F, Riva D, Trecate G, et al. Diffuse pontine gliomas in children: changing strategies, changing results? A mono-institutional 20-year experience. J Neurooncol. 2008 May;87(3):355-361. doi: 10.1007/s11060-008-9525-5.
- Frappaz D, Schell M, Thiesse P, Marec-Bérard P, Mottolese C, Perol D, et al. Preradiation chemotherapy may improve survival in pediatric diffuse intrinsic brainstem gliomas: final results of BSG 98 prospective trial. Neuro Oncol. 2008 Aug;10(4):599-607. doi: 10.1215/15228517-2008-029.
- Couldwell WT, Hinton DR, Surnock AA, DeGiorgio CM, Weiner LP, Apuzzo ML, et al. Treatment of recurrent malignant gliomas with chronic oral high-dose tamoxifen. Clin Cancer Res. 1996 Apr;2(4):619-622.
- Narayana A, Kunnakkat S, Chacko-Mathew J, Gardner S, Karajannis M, Raza S, et al. Bevacizumab in recurrent high-grade pediatric gliomas. Neuro Oncol. 2010 Sep;12(9):985-990. doi: 10.1093/neuonc/noq033.
- Bartels U, Wolff J, Gore L, Dunkel I, Gilheeney S, Allen J, et al. Phase 2 study of safety and efficacy of nimotuzumab in pediatric patients with progressive diffuse intrinsic pontine glioma. Neuro Oncol. 2014 Nov;16(11):1554-1559. doi: 10.1093/neuonc/nou091.
- Pollack IF, Stewart CF, Kocak M, Poussaint TY, Broniscer A, Banerjee A, et al. A phase II study of gefitinib and irradiation in children with newly diagnosed brainstem gliomas: a report from the Pediatric Brain Tumor Consortium. Neuro Oncol. 2011 Mar;13(3):290-297. doi: 10.1093/neuonc/noq199.
- Geoerger B, Hargrave D, Thomas F, Ndiaye A, Frappaz D, Andreiuolo F, et al; ITCC (Innovative Therapies for Children with Cancer) European Consortium. Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors. Neuro Oncol. 2011 Jan;13(1):109-118. doi: 10.1093/neuonc/noq141.
- Broniscer A, Jia S, Mandrell B, Hamideh D, Huang J, Onar-Thomas A, et al. Phase 1 trial, pharmacokinetics, and pharmacodynamics of dasatinib combined with crizotinib in children with recurrent or progressive high-grade and diffuse intrinsic pontine glioma. Pediatr Blood Cancer. 2018 Jul;65(7):e27035. doi: 10.1002/pbc.27035.
- Vitanza NA, Monje M. Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials. Curr Treat Options Neurol. 2019 Jul 10;21(8):37. doi: 10.1007/s11940-019-0577-y.
- Vitanza NA, Wilson AL, Huang W, Seidel K, Brown C, Gustafson JA, et al. Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety. Cancer Discov. 2023 Jan 9;13(1):114-131. doi: 10.1158/2159-8290.CD-22-0750.
- Fried I, Lossos A, Ben Ami T, Dvir R, Toledano H, Ben Arush, et al. Preliminary results of immune modulating antibody MDV9300 (pidilizumab) treatment in children with diffuse intrinsic pontine glioma. J Neurooncol. 2018 Jan;136(1):189-195. doi: 10.1007/s11060-017-2643-1.
- El-Khouly FE, Veldhuijzen van Zanten SEM, Santa-Maria Lopez V, Hendrikse NH, Kaspers GJL, Loizos G, et al. Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand? J Neurooncol. 2019 Oct;145(1):177-184. doi: 10.1007/s11060-019-03287-9.
- Mount CW, Majzner RG, Sundaresh S, Arnold EP, Kadapakkam M, Haile S, et al. Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas. Nat Med. 2018 May;24(5):572-579. doi: 10.1038/s41591-018-0006-x.
- Warren KE. Beyond the Blood:Brain Barrier: The Importance of Central Nervous System (CNS) Pharmacokinetics for the Treatment of CNS Tumors, Including Diffuse Intrinsic Pontine Glioma. Front Oncol. 2018 Jul 3;8:239. doi: 10.3389/fonc.2018.00239.
- Warren KE. Diffuse intrinsic pontine glioma: poised for progress. Front Oncol. 2012 Dec 28;2:205. doi: 10.3389/fonc.2012.00205.
- Vengoji R, Ponnusamy MP, Rachagani S, Mahapatra S, Batra SK, Shonka N, Macha MA. Novel therapies hijack the blood-brain barrier to eradicate glioblastoma cancer stem cells. Carcinogenesis. 2019 Mar 12;40(1):2-14. doi: 10.1093/carcin/bgy171.
- Gwak HS, Park HJ. Developing chemotherapy for diffuse pontine intrinsic gliomas (DIPG). Crit Rev Oncol Hematol. 2017 Dec;120:111-119. doi: 10.1016/j.critrevonc.2017.10.013.
- Foley CP, Rubin DG, Santillan A, Sondhi D, Dyke JP, Crystal RG, et al. Intra-arterial delivery of AAV vectors to the mouse brain after mannitol mediated blood brain barrier disruption. J Control Release. 2014 Dec 28;196:71-78. doi: 10.1016/j.jconrel.2014.09.018.
- Chu PC, Chai WY, Tsai CH, Kang ST, Yeh CK, Liu HL. Focused Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced Magnetic-Resonance Imaging. Sci Rep. 2016 Sep 15;6:33264. doi: 10.1038/srep33264.
- Parekh K, LeBlang S, Nazarian J, Mueller S, Zacharoulis S, Hynynen K, Powlovich L. Past, present and future of Focused Ultrasound as an adjunct or complement to DIPG/DMG therapy: A consensus of the 2021 FUSF DIPG meeting. Neoplasia. 2023 Mar;37:100876. doi: 10.1016/j.neo.2023.100876.
- McCrea HJ, Ivanidze J, O'Connor A, Hersh EH, Boockvar JA, Gobin YP, et al. Intraarterial delivery of bevacizumab and cetuximab utilizing blood-brain barrier disruption in children with high-grade glioma and diffuse intrinsic pontine glioma: results of a phase I trial. J Neurosurg Pediatr. 2021 Aug 6;28(4):371-379. doi: 10.3171/2021.3.PEDS20738.
- Kang JH, Desjardins A. Convection-enhanced delivery for high-grade glioma. Neurooncol Pract. 2021 Nov 20;9(1):24-34. doi: 10.1093/nop/npab065.
- Nwagwu CD, Immidisetti AV, Jiang MY, Adeagbo O, Adamson DC, Carbonell AM. Convection Enhanced Delivery in the Setting of High-Grade Gliomas. Pharmaceutics. 2021 Apr 15;13(4):561. doi: 10.3390/pharmaceutics13040561.
- Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2076-2080. doi: 10.1073/pnas.91.6.2076.
- Lewis O, Woolley M, Johnson D, Rosser A, Barua NU, Bienemann AS, et al. Chronic, intermittent convection-enhanced delivery devices. J Neurosci Methods. 2016 Feb 1;259:47-56. doi: 10.1016/j.jneumeth.2015.11.008.
- Chen MY, Lonser RR, Morrison PF, Governale LS, Oldfield EH. Variables affecting convection-enhanced delivery to the striatum: a systematic examination of rate of infusion, cannula size, infusate concentration, and tissue-cannula sealing time. J Neurosurg. 1999 Feb;90(2):315-320. doi: 10.3171/jns.1999.90.2.0315.
- Casanova F, Carney PR, Sarntinoranont M. Influence of needle insertion speed on backflow for convection-enhanced delivery. J Biomech Eng. 2012 Apr;134(4):041006. doi: 10.1115/1.4006404.
- Varenika V, Dickinson P, Bringas J, LeCouteur R, Higgins R, Park J, et al. Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery. J Neurosurg. 2008 Nov;109(5):874-80. doi: 10.3171/JNS/2008/109/11/0874.
- Zhou Z, Singh R, Souweidane MM. Convection-Enhanced Delivery for Diffuse Intrinsic Pontine Glioma Treatment. Curr Neuropharmacol. 2017;15(1):116-128. doi: 10.2174/1570159x14666160614093615.
- D'Amico RS, Aghi MK, Vogelbaum MA, Bruce JN. Convection-enhanced drug delivery for glioblastoma: a review. J Neurooncol. 2021 Feb;151(3):415-427. doi: 10.1007/s11060-020-03408-9.
- Hollingworth M, Zacharoulis S. Infusion-related side-effects during convection enhanced delivery for brainstem-diffuse midline glioma/diffuse intrinsic pontine glioma. J Neurooncol. 2022 Sep;159(2):417-424. doi: 10.1007/s11060-022-04077-6.
- Чернов В.И., Брагина О.Д., Синилкин И.Г., Медведева А.А., Зельчан Р.В. Радионуклидная тераностика злокачественных образований. Вестник рентгенологии и радиологии. 2016;97(5):306-313. doi: 10.20862/0042-4676-2016-97-5-306-313.
- Bander ED, Ramos AD, Wembacher-Schroeder E, Ivasyk I, Thomson R, Morgenstern PF, Souweidane MM. Repeat convection-enhanced delivery for diffuse intrinsic pontine glioma. J Neurosurg Pediatr. 2020 Sep 25;26(6):661-666. doi: 10.3171/2020.6.PEDS20280.
- Szychot E, Walker D, Collins P, Hyare H, Shankar A, Bienemann A, et al. Clinical experience of convection-enhanced delivery (CED) of carboplatin and sodium valproate into the pons for the treatment of diffuse intrinsic pontine glioma (DIPG) in children and young adults after radiotherapy. Int J Clin Oncol. 2021 Apr;26(4):647-658. doi: 10.1007/s10147-020-01853-0.
- Szychot E, Bhagawati D, Sokolska MJ, Walker D, Gill S, Hyare H. Evaluating drug distribution in children and young adults with diffuse midline glioma of the pons (DIPG) treated with convection-enhanced drug delivery. Front Neuroimaging. 2023 Feb 28;2:1062493. doi: 10.3389/fnimg.2023.1062493.
- Veldhuijzen van Zanten SEM, Baugh J, Chaney B, De Jongh D, Sanchez Aliaga E, et al; members of the SIOPE DIPG Network. Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease. J Neurooncol. 2017 Apr;132(2):255-266. doi: 10.1007/s11060-016-2363-y.
- Gao L, Shi C, Yang Z, Jing W, Han M, Zhang J, Zhang C, Tang C, Dong Y, Liu Y, Chen C, Jiang X. Convection-enhanced delivery of nanoencapsulated gene locoregionally yielding ErbB2/Her2-specific CAR-macrophages for brainstem glioma immunotherapy. J Nanobiotechnology. 2023 Feb 20;21(1):56. doi: 10.1186/s12951-023-01810-9.
- Кувшинов А.Ю., Волошин С.В., Кузяева А.А., Шуваев В.А., Михалева М.А., Мартынкевич И. С. и др. Современные представления о CAR T-клеточной терапии. Вестник гематологии. 2019;15(2):4-11.
- Warren K, Jakacki R, Widemann B, Aikin A, Libucha M, Packer R, et al. Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group. Cancer Chemother Pharmacol. 2006 Sep;58(3):343-347. doi: 10.1007/s00280-005-0172-7.
- Sethi R, Allen J, Donahue B, Karajannis M, Gardner S, Wisoff J, et al. Prospective neuraxis MRI surveillance reveals a high risk of leptomeningeal dissemination in diffuse intrinsic pontine glioma. J Neurooncol. 2011 Mar;102(1):121-127. doi: 10.1007/s11060-010-0301-y.
- Buczkowicz P, Bartels U, Bouffet E, Becher O, Hawkins C. Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications. Acta Neuropathol. 2014 Oct;128(4):573-581. doi: 10.1007/s00401-014-1319-6.
- Vinci M, Burford A, Molinari V, Kessler K, Popov S, Clarke M, et al. Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells. Nat Med. 2018 Aug;24(8):1204-1215. doi: 10.1038/s41591-018-0086-7.