Clinical and epidemiological features of neuro-syphilis in Altai territory (1999-2016)

Purpose: identification of tendencies of development of incidence of a neurosyphilis and structures of clinical forms of a late neurosyphilis in Altai Territory. Material and Methods. Materials of forms of the state statistical overseeing of 1999-2016 across Altai Territory, official statistical materials of the Department of monitoring, the analysis and strategic development of health care, Federal State Budgetary Institution Central Research and Development Institute of the Organization and Informatization of Health Care, contemporary records of medical institutions of Altai Territory are analysed. Results. The carried-out retrospective analysis of incidence of a lues in Altai Territory for the 18-year period of observations revealed tendencies to decrease in primary incidence of a lues with simultaneous increase in structure of late forms, including a late neurosyphilis that completely confirmed the model of development of epidemic process constructed earlier by authors. In structure of forms of a late neurosyphilis without symptomless neurosyphilis, symptomless meningitis and meningovascular forms of neurosyphilis came to light more often. Conclusion. The clinical picture of late forms of a neurosyphilis is mainly without symptoms character now. Among demonstrative forms the meningovascular forms as a predictor of cerebrovascular pathology at working-age is registered more often.