Mechanisms of docosahexaenoic acid influence on cognitive functions at neuroinflammation

Docosahexaenoic acid (DHA) is one of the most important structural and functional components of the central nervous system. The decrease in its contents in a brain accompanying aging processes is often connected with cognitive deficiency and development of neurodegenerate diseases. A research objective - an assessment the influence of DHA on cognitive functions at the peripheral induced neuroinflammation. Experiment was made on mice males age by 3 months. DHA entered orally in the form of ethyl air within 6 weeks in a dosage 200 mkg/kg. Lack of decrease in an indicator of working memory in group of the animals receiving DHA at induction of a neuroinflammation is shown. Decrease in an expression of GF AP proteins and IL-1beta at a neuroinflammation under the influence of DHA is established.