Metabolic disorders in the acute period of COVID-19

Components of metabolic syndrome such as arterial hypertension, type 2 DM and obesity are common and significantly increase the risk of hospitalization and mortality in patients with COVID-19. Aim of the study: to determine the nature of metabolic abnormalities in patients with COVID-19 during the acute phase of the disease. The article presents the results of studying the character of metabolic disorders in patients with COVID-19 in the acute phase of the disease. The data of 31 patients in the acute period of corona-virus infection caused by COVID-19 were used in the study. The mean age of the patients was 56.4±12.8 years (32 to 80 years), among them 13 (41.9%) were males and 18 (58.1%) were females. The obtained data indicate that obesity and dyslipidemia in the form of elevated levels are more common in patients with moderately severe course of the disease. But at the same time, some metabolic disorders are also 1.2-1.6 times more frequent in patients with moderate course of coronavirus infection compared to mild course (respectively BP≥140/90 mm. Hg: 23.5% vs. 14.3%; TG ≥1.7 mmol/L: 47.1% vs. 28.6%; HDL <1.0 mmol/L: 64.7 vs. 28.6%; fasting glucose ≥6.1 mmol/L: 35.3% vs. 28.6%). Thus, the presence of metabolic disorders such as obesity, arterial hypertension, dyslipidemia, and impaired carbohydrate metabolism are associated with a more severe course of coronavirus infection.