Metabolic status of cows with follicular cystic ovarian disease

The metabolic status of dairy cows diagnosed with follicular cystic ovarian disease was studied. The object of the study was Holstein cows of black and white breed (blood content over 75%) of 2-3 lactation, which were diagnosed with follicular ovarian cyst during a gynecological medical examination. The study material was blood, taken from the subcaudal vein, using a vacuum method. Indicators of lipid, protein, and carbon-water metabolism, as well as the hormone progesterone, were determined in the blood. It was found that the features of lipid metabolism in cows with follicular cysts are associated with a decrease in the amount of triacylglycerides (TAG) in the blood by 35.00% and an increase in total cholesterol (TC) by 10.20% compared to the normal limits. The values of the variation coefficients of TAG and TC are 7.16 and 5.16%, indicating the uniformity of their changes in the selected group of cows. Carbohydrate metabolism, assessed by the amount of glucose, lactate and LDH activity, is formed under conditions of an increase in the glucose level by 1.26 times, compared to the norm, and fluctuations in the amount of lactate and LDH activity within the lower limits of the norm. The values of the variation coefficients (Cv) of carbohydrate metabolism indicators are 0.48-7.98%. Protein metabolism in the body of cows with ovarian follicular cysts is formed under conditions of fluctuations in the amount of total protein in the blood serum within 78.50 - 81.60 g / l (Cv = 1.69%). At the same time, the concentration of albumin and ceruloplasmin decreases, compared to the norm, by 1.10 and 14.59 times, the activity of transamination enzymes (ALT, AST) increases by 1.31 and 2.21 times. The value of the variation coefficient of biochemical parameters does not exceed 10%, with the exception of ceruloplasmin. The level of progesterone in the blood of cows is 1.30 ± 0.03 nmol/l (Cv = 6.28%) or 0.41 ± 0.02 ng/ml, which confirms the presence of follicular cysts in the ovaries. The concentration of progesterone is statistically significantly associated with the amount of total cholesterol (r = 0.90 ± 0.02); glucose (r=0.83±0.20); albumins (r=0.83±0.13); urea r=0.76±0.23) and AST activity r=-0.77±0.23).