COVID-19 associated myocarditis: mechanisms of pathogenesis, problems of diagnostics (review)

The review summarizes actual information on inflammatory myocardial injury in COVID-19. The most update works from 2020–2021 were used as the literature sources, as well as earlier research containing fundamental information on the relevant topic. The substantial information is reflected in the review. Used queries: myocarditis, myocardial injury, COVID-19 — in the search engines PubMed / MedLine, eLibrary. The analysis of current international literature has demonstrated convincing evidence of the possible development of myocarditis in case of new coronavirus infection. The histological verification of myocardial injury associated with COVID-19 presents significant difficulties, since in conditions of a severe course of infection; it is not always possible to perform endomyocardial biopsy. In this regard, the statistics do not reflect complete information on the prevalence of COVID-19 associated myocarditis. All mechanisms of the pathogenesis of inflammatory myocardial injury have not been completely clarified. Due to the ambiguity of the prognosis of patients with COVID-19 associated myocarditis, further study of the problem is required