Миокардит при инфекции COVID-19: патогенетические механизмы, сложности диагностики (обзор)

Автор: Сергеева В. А., Липатова Т. Е.

Журнал: Саратовский научно-медицинский журнал @ssmj

Рубрика: Кардиология

Статья в выпуске: 3 т.17, 2021 года.

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В обзоре обобщена актуальная информация по воспалительному миокардиальному повреждению при инфекции COVID-19. В качестве литературных источников использованы наиболее актуальные работы 2020–2021 гг., а также более ранние источники, содержащие фундаментальные сведения соответствующей тематики; наиболее значимая информация по обсуждаемой проблеме приведена в статье (всего 50 работ). Использованы запросы: «миокардит», «миокардиальное повреждение», «COVID-19» — в поисковых системах PubMed / MedLine, eLibrary. Анализ актуальной международной литературы продемонстрировал убедительные доказательства возможного развития миокардита в рамках новой коронавирусной инфекции. Значительные сложности представляет гистологическая верификация миокардиального повреждения, ассоциированного с COVID-19, так как в условиях тяжелого течения инфекции выполнение эндомиокардиальной биопсии не всегда возможно. В связи с этим статистические данные не отражают полной информации о распространенности миокардитов, ассоциированных с COVID-19. Не окончательно прояснены все механизмы патогенеза воспалительного повреждения миокарда. Для улучшения прогноза пациентов с миокардитом при инфекции COVID-19 требуется дальнейшее изучение проблемы и выработка унифицированных подходов к диагностике и лечению

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COVID-19, SARS-CoV-2, миокардит, миокардиальное повреждение, сердечно-сосудистая система.

Короткий адрес: https://sciup.org/149138157

IDR: 149138157

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