Modulated electrohyperthermia (oncothermia) in treatment of malignances of various localization (short literature review)

Modulated electrohyperthermia (oncothermy, mEGT) is a method of anti-tumor treatment based on the effect of electromagnetic fields on malignant cells. It provides local exposure to an alternating 3 high - frequency electric field (13.56 MHz) modulated by fractal harmonic vibrations in the frequency range of 0-5 kHz, performed by means of asymmetric electrodes capacitive conjugation. The article provides an overview of international clinical studies, highlighting mEHT treatment options for malignances of various localizations, published in 2010 - 2020 in Russian Index of Scientific Citation system, PubMed, Cochrane database, Russian and international journals, international congresses and conferences. The analysis of the data available in the literature allows to conclude that mEHT is a promising option for radio- and chemo sensitization, with a significant positive effect on conventional treatment results in patients with an unfavorable prognosis of the oncological disease. Goals and objectives: to expand the indications for the practical application of the technique at the stages of primary radiation and drug treatment in patients with tumors of various localizations.