The morpho-functional diagnostics of age-related neurodystrophic changing in the organism, which preceded sudden cardiac death

The mechanism of pathogenesis of sudden cardiac death (SCD) under the conditions of earlier changes of CNS and neurodistrophic body disorders were investigated in the cardio complex as a result of the morphofunctional studies about the neurogenic nature of heart diseases developed in the doctrine by A.I. Myasnikov. It was found that from 35-40 years of age there is a sympathectomy of the cardiovascular system develops in connection with the implementation of phenomenon of the age increase of the involutive changes in the sympathetic division of the autonomic nervous system, and according to W.B.Cannon's law one observes a continuous increase in the sensitivity to the humoral factors of enervated myocardium up till the emergence of the atrial fibrillation. The degree of innervation change in the cardiovascular system and the susceptibility to SCD central nervous system increase mainly during the active course of coronary heart disease. The major goal of prevention and control of SCD is a systematic diagnosis of the population on the pre-hospital level; and it is required to carry out an ambulatory analysis of the state of the nervous system by means of the method of time-frequency spectral analysis of heart rate variability in case of coronary artery disease detection on the early stages of orthostatic tests because the reduction of low-frequency of the power spectrum of cardio is detected after the age of forty...