Morphological features of thymus in the conditions of the wound process of the skin

The article describes the morphological features of the thymus in the dynamics of thermal burn injury of the skin. In the course of the study, it was revealed that under conditions of burn exposure, animals developed accidental involution of the thymus, characterizing the scattered location of thymocytes in the cortical substance and smoothing of the cortico-medullary border. The increase in the size of nuclei and cells was accompanied by edema of the interlobar stroma, expansion of the intralobular perivascular spaces against the background of blood vessel fullness and erythrocyte diapedesis. Revealed destructive-dystrophic changes of thymus against the background of skin trauma confirm the dependence of sensitization of the cellular organization of immunocompetent organs on the temporary periodization of the post-traumatic burn process.