QT-interval disorder and structural and functional myocardial remodeling in patients with heart micro anomalies

To assess the incidence and character of QT interval disorders in patients with heart micro anomalies and reveal the correlation between the structural and functional myocardial remodeling and QT interval, 111 patients (70 males and 41 females, mean 22.6±0.3 years) were included into the study. A statistically significant increased incidence of QT interval disorder was observed for the following heart micro anomalies: bicuspid aortic valve, mitral valve prolapse, tricuspid valve prolapse, open oval gap, and abnormally located chordae. In patients with heart micro anomalies and QT interval disorder as compared to normal QT interval, the peculiarities of structural and functional myocardial remodeling, e.g. increased left ventricular mass index were revealed.