Neuroimaging correlates of different stages of hypertensive dyscirculatory encephalopathy

The objective was to present the neuroimaging correlates of different stages of hypertensive dyscirculatory encephalopathy (HDE).Material and methods. We examined 132 patients with HDE. Patients were divided into groups according to the stages of the HDE. Clinical manifestations in 37 patients met the HDE stage I, 51 patients - HDE stage II, 44 man - HDE stage III. All patients underwent magnetic resonance tomography apparatus Siemens Magnetom Symphony equipped with a superconducting magnetic system with field strength of 1.5 Tesla. Images were obtained in axial, sagittal and coronal projections using T2 pulse sequences with parameters TR/TE 4000/107, T1 with parameters TR/TE 400/13, program FLAIR with parameters TR/TE 9000/116. The slice thickness is 5 mm.The results of the study and their discussion. When the HDE stage I focal changes were defined mostly in the white matter of the frontal lobes of the brain and located subcortical, when the HDE stage II - in the white matter of the frontal and parietal lobes and subcortical periventricular, as well as in the subcortical nuclei and the thalamus. When the HDE stage III focal change was seen in the frontal, parietal, temporal, occipital and insular lobes and subcortical periventricular, as well as in subcortical nuclei, the thalamus, the midbrain, varoliev the bridge and the cerebellum. In patients with stage I HDE dominates the rear lamares with much less pronounced lateral and front missing, the HDE in patients with stages II and III dominates the front lachares.Conclusions. Such description allows to more accurately determine the stage of the HDE. Further etiopathogenetical and rehabilitation activities should be conducted according to established data determining the degree of damage of the white matter of the brain in this disease.