Parameters of blood microcirculation in patients with acute schizophrenia and delirium tremens in a comparative aspect

The pathogenesis of microcirculation disorders in mental and narcological disorders is not well understood. The aim of the work is to study the state of microcirculation of blood by the method of laser Doppler flowmetry in patients in a psychotic state with schizophrenia and with alcohol withdrawal syndrome with delirium in a comparative aspect. 40 patients with schizophrenia and 25 patients with delirium tremens in an acute psychotic state and after 2 weeks of therapy are examined using a laser blood flow analyzer. The control group consists of 35 healthy volunteers. General and systemic microcirculation disorders in patients with acute psychotic state in schizophrenia and delirium tremens in the form of accelerated blood flow per unit of time and excessive strengthening of local mechanisms of its regulation are established. At the same time, changes in microcirculation indices persist even after two weeks of therapy, having probably a longer pathological effect than the course of acute psychosis itself.